Literature DB >> 24083851

Transoral robotic surgery experience in 44 cases.

Ray G F Blanco1, Carole Fakhry, Patrick K Ha, Keri Ryniak, Barbara Messing, Joseph A Califano, John R Saunders.   

Abstract

OBJECTIVE: To report a single institution's experience with transoral robotic surgery (TORS) and its clinical outcomes. This was a retrospective study carried out at a university-affiliated teaching hospital. SUBJECTS AND METHODS: Forty-four consecutive TORS patients with benign and malignant diseases were reviewed. Data on demographics, clinical parameters, and diet were collected. Surgical margins, local and regional recurrence, distant metastasis, 2-year disease-free survival rate, and 2-year survival data were reviewed for the malignant cases.
RESULTS: Nine benign and 35 proven squamous cell carcinoma (SCCA) cases underwent TORS. The set-up time was 17.12 minutes (range, 10-40 minutes), and operative time was 53 minutes (range, 10-300 minutes). Average length of stay was 2.5 days. There were seven (6.8%) grade 3 surgical complications. Surgical infection rate was 2.3%. Benign cases were on a regular diet after TORS. Of the malignant cases, 94% were taking peroral diet immediately after the TORS procedure. There were no intraoperative complications and no 30-day postoperative mortalities. The mean follow-up time was 25.2 months (range, 16-38 months) for malignant disease. The SCCA sites were in the oropharynx (30/35), larynx (2/35), and unknown primary with neck metastasis (3/35). Unknown primary patients were excluded in the surgical margin analyses. Negative margins were achieved in 91% of cases. The local and regional recurrence rates were 6.3% (2/32) and 3.1% (1/32), respectively. Two patients (6.3%) developed distant metastasis. Oropharyngeal SCCA cases were reviewed, of which 23 were human papillomavirus (HPV)/p16 positive and 7 were HPV/p16 negative. The 2-year actual survival for HPV-positive and -negative patients was 96% (22/23) and 86% (6/7), respectively. The 2-year disease-free survival for HPV-positive and -negative cases was 91% (21/23) and 71.4% (5/7), respectively. All malignant cases that underwent TORS received postoperative adjuvant therapy.
CONCLUSIONS: TORS is a safe procedure with minimal complications and acceptable clinical and functional outcomes.

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Year:  2013        PMID: 24083851     DOI: 10.1089/lap.2013.0261

Source DB:  PubMed          Journal:  J Laparoendosc Adv Surg Tech A        ISSN: 1092-6429            Impact factor:   1.878


  9 in total

1.  Assessment of Surgical Learning Curves in Transoral Robotic Surgery for Squamous Cell Carcinoma of the Oropharynx.

Authors:  William G Albergotti; William E Gooding; Mark W Kubik; Mathew Geltzeiler; Seungwon Kim; Umamaheswar Duvvuri; Robert L Ferris
Journal:  JAMA Otolaryngol Head Neck Surg       Date:  2017-06-01       Impact factor: 6.223

2.  Transoral surgery using a novel single-port flexible endoscope system.

Authors:  Magis Mandapathil; Brandon Greene; Thomas Wilhelm
Journal:  Eur Arch Otorhinolaryngol       Date:  2014-07-14       Impact factor: 2.503

3.  Transoral robotic surgery for the benefit of patients with head and neck cancer of unknown primary: our experience at St George's University Hospital, London.

Authors:  R Mistry; A Walker; D Kim; E Ofo
Journal:  Ann R Coll Surg Engl       Date:  2020-04-29       Impact factor: 1.891

Review 4.  Transoral robotic surgery and intensity-modulated radiotherapy in the treatment of the oropharyngeal carcinoma: a systematic review and meta-analysis.

Authors:  Armando De Virgilio; Andrea Costantino; Giuseppe Mercante; Raul Pellini; Fabio Ferreli; Luca Malvezzi; Giovanni Colombo; Giovanni Cugini; Gerardo Petruzzi; Giuseppe Spriano
Journal:  Eur Arch Otorhinolaryngol       Date:  2020-07-21       Impact factor: 2.503

5.  A novel approach emphasising intra-operative superficial margin enhancement of head-neck tumours with narrow-band imaging in transoral robotic surgery.

Authors:  C Vicini; F Montevecchi; G D'Agostino; A DE Vito; G Meccariello
Journal:  Acta Otorhinolaryngol Ital       Date:  2015-06       Impact factor: 2.124

Review 6.  Robotic surgical systems in maxillofacial surgery: a review.

Authors:  Hang-Hang Liu; Long-Jiang Li; Bin Shi; Chun-Wei Xu; En Luo
Journal:  Int J Oral Sci       Date:  2017-06       Impact factor: 6.344

7.  A systematic review on Transoral robotic surgery (TORS) for carcinoma of unknown primary origin: Has tongue base mucosectomy become indispensable?

Authors:  Stijn van Weert; Johannes A Rijken; Francesca Plantone; Elisabeth Bloemena; Marije R Vergeer; Birgit I Lissenberg-Witte; C René Leemans
Journal:  Clin Otolaryngol       Date:  2020-05-25       Impact factor: 2.597

Review 8.  The role of transoral robotic surgery, transoral laser microsurgery, and lingual tonsillectomy in the identification of head and neck squamous cell carcinoma of unknown primary origin: a systematic review.

Authors:  Terence S Fu; Andrew Foreman; David P Goldstein; John R de Almeida
Journal:  J Otolaryngol Head Neck Surg       Date:  2016-05-04

9.  Finding/identifying primaries with neck disease (FIND) clinical trial protocol: a study integrating transoral robotic surgery, histopathological localisation and tailored deintensification of radiotherapy for unknown primary and small oropharyngeal head and neck squamous cell carcinoma.

Authors:  John R de Almeida; Christopher W Noel; Maria Veigas; Rosemary Martino; Douglas B Chepeha; Scott V Bratman; David P Goldstein; Aaron R Hansen; Eugene Yu; Ur Metser; Ilan Weinreb; Bayardo Perez-Ordonez; Wei Xu; John Kim
Journal:  BMJ Open       Date:  2019-12-30       Impact factor: 2.692

  9 in total

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