Literature DB >> 24081545

Laparoscopic extralevator abdominoperineal excision of the rectum: short-term outcomes of a prospective case series.

S L Kipling1, K Young, J D Foster, N J Smart, A E Hunter, E Cooper, N K Francis.   

Abstract

BACKGROUND: Laparoscopic approaches for the resection of low rectal cancer and the extralevator technique for abdominoperineal excision are both becoming increasingly popular. There are little published data regarding the combined application of these techniques to the resection of low rectal tumours. The aim of this study was to assess the feasibility of such an approach and to appraise short-term outcomes in a consecutive series of patients undergoing laparoscopic extralevator abdominoperineal excision (ELAPE).
METHODS: Consecutive patients undergoing laparoscopic ELAPE at our institution between 2008 and 2011 were identified from a prospectively maintained database. The abdominal phase of the operation was performed laparoscopically, and following extralevator resection, the perineum was reconstructed using a biologic mesh. All patients were enrolled in an enhanced recovery programme.
RESULTS: Of 166 patients undergoing radical resection of rectal cancer at our institution between 2008 and 2011, 28 underwent laparoscopic ELAPE. Median age was 70 years, median body mass index was 27.5 kg/m(2), and 71% were male. The conversion rate to laparotomy was 18%. Three patients (10.8%) had circumferential resection margins <1 mm; no intraoperative tumour perforation occurred. The median length of stay was 7 days, with a 30-day readmission rate of 21% and no 30-day mortality. Post-operative perineal wound complications occurred in 25%. At median 38-month follow-up (range 23-66 months), overall survival was 75%, disease-free survival was 71%, and there were three local recurrences (11%).
CONCLUSIONS: Laparoscopic extralevator abdominoperineal excision can be safely performed without compromising short-term outcomes.

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Year:  2013        PMID: 24081545     DOI: 10.1007/s10151-013-1071-2

Source DB:  PubMed          Journal:  Tech Coloproctol        ISSN: 1123-6337            Impact factor:   3.781


  32 in total

1.  Oncological outcome after laparoscopic abdominoperineal excision of the rectum.

Authors:  M T Jefferies; M D Evans; J Hilton; T V Chandrasekaran; J Beynon; U Khot
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2.  Randomized clinical trial comparing laparoscopic and open surgery for colorectal cancer within an enhanced recovery programme.

Authors:  P M King; J M Blazeby; P Ewings; P J Franks; R J Longman; A H Kendrick; R M Kipling; R H Kennedy
Journal:  Br J Surg       Date:  2006-03       Impact factor: 6.939

3.  Primary perineal wound closure after preoperative radiotherapy and abdominoperineal resection has a high incidence of wound failure.

Authors:  Kelli M Bullard; Judith L Trudel; Nancy N Baxter; David A Rothenberger
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4.  Low rectal cancer: a call for a change of approach in abdominoperineal resection.

Authors:  Iris D Nagtegaal; Cornelius J H van de Velde; Corrie A M Marijnen; Jan H J M van Krieken; Philip Quirke
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5.  Abdominoperineal excision of the rectum--an endangered operation. Norman Nigro Lectureship.

Authors:  R J Heald; R K Smedh; A Kald; R Sexton; B J Moran
Journal:  Dis Colon Rectum       Date:  1997-07       Impact factor: 4.585

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Review 7.  Reconstruction of the perineum following extralevator abdominoperineal excision for carcinoma of the lower rectum: a systematic review.

Authors:  J D Foster; S Pathak; N J Smart; G Branagan; R J Longman; M G Thomas; N Francis
Journal:  Colorectal Dis       Date:  2012-09       Impact factor: 3.788

8.  Short-term endpoints of conventional versus laparoscopic-assisted surgery in patients with colorectal cancer (MRC CLASICC trial): multicentre, randomised controlled trial.

Authors:  Pierre J Guillou; Philip Quirke; Helen Thorpe; Joanne Walker; David G Jayne; Adrian M H Smith; Richard M Heath; Julia M Brown
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9.  Evidence of the oncologic superiority of cylindrical abdominoperineal excision for low rectal cancer.

Authors:  Nicholas P West; Paul J Finan; Claes Anderin; Johan Lindholm; Torbjorn Holm; Philip Quirke
Journal:  J Clin Oncol       Date:  2008-06-09       Impact factor: 44.544

10.  The mesorectum in rectal cancer surgery--the clue to pelvic recurrence?

Authors:  R J Heald; E M Husband; R D Ryall
Journal:  Br J Surg       Date:  1982-10       Impact factor: 6.939

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Journal:  Tech Coloproctol       Date:  2014-11-04       Impact factor: 3.781

2.  Re: staying on target-reply to comments by Loyal et al.

Authors:  J D Foster; N J Smart; N K Francis
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3.  Extralevator versus standard abdominoperineal excision for rectal cancer.

Authors:  S K Perdawood; T Lund
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4.  Local recurrence after 'standard' abdominoperineal resection: do we really need ELAPE?

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Review 5.  Biologic Mesh Reconstruction of the Pelvic Floor after Extralevator Abdominoperineal Excision: A Systematic Review.

Authors:  Nasra N Alam; Sunil K Narang; Ferdinand Köckerling; Ian R Daniels; Neil J Smart
Journal:  Front Surg       Date:  2016-02-16

Review 6.  Extralevator abdominoperineal excision for advanced low rectal cancer: Where to go.

Authors:  Yu Tao; Jia-Gang Han; Zhen-Jun Wang
Journal:  World J Gastroenterol       Date:  2020-06-14       Impact factor: 5.742

7.  Oncological outcomes of abdominoperineal resection for the treatment of low rectal cancer: A retrospective review of a single UK tertiary centre experience.

Authors:  Anwar Hussain; Fahad Mahmood; Andrew D W Torrance; Helen Clarke; Cordelia Howitt; Robin Dawson
Journal:  Ann Med Surg (Lond)       Date:  2018-06-26

8.  Application of modified primary closure of the pelvic floor in laparoscopic extralevator abdominal perineal excision for low rectal cancer.

Authors:  Yan-Lei Wang; Xiang Zhang; Jia-Jia Mao; Wen-Qiang Zhang; Hao Dong; Fan-Pei Zhang; Shuo-Hui Dong; Wen-Jie Zhang; Yong Dai
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9.  Long-term outcomes of laparoscopic Extralevator Abdominoperineal excision with modified position change for low rectal Cancer treatment.

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Review 10.  Porcine dermis implants in soft-tissue reconstruction: current status.

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