Literature DB >> 2407844

Molecular modeling software and methods for medicinal chemistry.

N C Cohen1, J M Blaney, C Humblet, P Gund, D C Barry.   

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Year:  1990        PMID: 2407844     DOI: 10.1021/jm00165a001

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


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  14 in total

1.  Combinatorial docking and combinatorial chemistry: design of potent non-peptide thrombin inhibitors.

Authors:  H J Böhm; D W Banner; L Weber
Journal:  J Comput Aided Mol Des       Date:  1999-01       Impact factor: 3.686

2.  Molecular-dynamics investigation of molecular flexibility in ligand binding.

Authors:  B Mao
Journal:  Biochem J       Date:  1992-11-15       Impact factor: 3.857

3.  The computer program LUDI: a new method for the de novo design of enzyme inhibitors.

Authors:  H J Böhm
Journal:  J Comput Aided Mol Des       Date:  1992-02       Impact factor: 3.686

Review 4.  Molecular recognition: models for drug design.

Authors:  R J Breckenridge
Journal:  Experientia       Date:  1991-12-01

5.  Pharmacophore development for antagonists at alpha 1 adrenergic receptor subtypes.

Authors:  J B Bremner; B Coban; R Griffith
Journal:  J Comput Aided Mol Des       Date:  1996-12       Impact factor: 3.686

6.  The statistical-thermodynamic basis for computation of binding affinities: a critical review.

Authors:  M K Gilson; J A Given; B L Bush; J A McCammon
Journal:  Biophys J       Date:  1997-03       Impact factor: 4.033

7.  Binding of a fibrinogen mimetic stabilizes integrin alphaIIbbeta3's open conformation.

Authors:  R R Hantgan; M Rocco; C Nagaswami; J W Weisel
Journal:  Protein Sci       Date:  2001-08       Impact factor: 6.725

8.  GenStar: a method for de novo drug design.

Authors:  S H Rotstein; M A Murcko
Journal:  J Comput Aided Mol Des       Date:  1993-02       Impact factor: 3.686

Review 9.  Strategies for indirect computer-aided drug design.

Authors:  G H Loew; H O Villar; I Alkorta
Journal:  Pharm Res       Date:  1993-04       Impact factor: 4.200

10.  SPROUT: a program for structure generation.

Authors:  V Gillet; A P Johnson; P Mata; S Sike; P Williams
Journal:  J Comput Aided Mol Des       Date:  1993-04       Impact factor: 3.686

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