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Literature DB >> 24074857

Cerebral organoids in a dish: progress and prospects.

Abstract

A three-dimensional culture of cortical tissues derived from pluripotent stem cells offers an opportunity to model human brain development and disorders. In a recent issue of Nature, Lancaster et al. describe a new method for generating cerebral organoids in a dish and use it to model microcephaly.

Entities: Disease Gene Species

Mesh：

Year: 2013 PMID： 24074857 PMCID： PMC5127703 DOI： 10.1016/j.cell.2013.09.010

Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582

9 in total

1. An intrinsic mechanism of corticogenesis from embryonic stem cells.

Authors: Nicolas Gaspard; Tristan Bouschet; Raphael Hourez; Jordane Dimidschstein; Gilles Naeije; Jelle van den Ameele; Ira Espuny-Camacho; Adèle Herpoel; Lara Passante; Serge N Schiffmann; Afsaneh Gaillard; Pierre Vanderhaeghen
Journal: Nature Date: 2008-08-17 Impact factor: 49.962

2. Self-organized formation of polarized cortical tissues from ESCs and its active manipulation by extrinsic signals.

Authors: Mototsugu Eiraku; Kiichi Watanabe; Mami Matsuo-Takasaki; Masako Kawada; Shigenobu Yonemura; Michiru Matsumura; Takafumi Wataya; Ayaka Nishiyama; Keiko Muguruma; Yoshiki Sasai
Journal: Cell Stem Cell Date: 2008-11-06 Impact factor: 24.633

3. Neurogenic radial glia in the outer subventricular zone of human neocortex.

Authors: David V Hansen; Jan H Lui; Philip R L Parker; Arnold R Kriegstein
Journal: Nature Date: 2010-03-25 Impact factor: 49.962

4. Pyramidal neurons derived from human pluripotent stem cells integrate efficiently into mouse brain circuits in vivo.

Authors: Ira Espuny-Camacho; Kimmo A Michelsen; David Gall; Daniele Linaro; Anja Hasche; Jérôme Bonnefont; Camilia Bali; David Orduz; Angéline Bilheu; Adèle Herpoel; Nelle Lambert; Nicolas Gaspard; Sophie Péron; Serge N Schiffmann; Michele Giugliano; Afsaneh Gaillard; Pierre Vanderhaeghen
Journal: Neuron Date: 2013-02-06 Impact factor: 17.173

5. Next-generation regenerative medicine: organogenesis from stem cells in 3D culture.

Authors: Yoshiki Sasai
Journal: Cell Stem Cell Date: 2013-05-02 Impact factor: 24.633

6. Modeling human cortical development in vitro using induced pluripotent stem cells.

Authors: Jessica Mariani; Maria Vittoria Simonini; Dean Palejev; Livia Tomasini; Gianfilippo Coppola; Anna M Szekely; Tamas L Horvath; Flora M Vaccarino
Journal: Proc Natl Acad Sci U S A Date: 2012-07-03 Impact factor: 11.205

7. Induction of pluripotent stem cells from adult human fibroblasts by defined factors.

Authors: Kazutoshi Takahashi; Koji Tanabe; Mari Ohnuki; Megumi Narita; Tomoko Ichisaka; Kiichiro Tomoda; Shinya Yamanaka
Journal: Cell Date: 2007-11-30 Impact factor: 41.582

8. Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses.

Authors: Yichen Shi; Peter Kirwan; James Smith; Hugh P C Robinson; Frederick J Livesey
Journal: Nat Neurosci Date: 2012-02-05 Impact factor: 24.884

9. Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling.

Authors: Stuart M Chambers; Christopher A Fasano; Eirini P Papapetrou; Mark Tomishima; Michel Sadelain; Lorenz Studer
Journal: Nat Biotechnol Date: 2009-03-01 Impact factor: 54.908

9 in total

22 in total

1. High-Content Screening in hPSC-Neural Progenitors Identifies Drug Candidates that Inhibit Zika Virus Infection in Fetal-like Organoids and Adult Brain.

Authors: Ting Zhou; Lei Tan; Gustav Y Cederquist; Yujie Fan; Brigham J Hartley; Suranjit Mukherjee; Mark Tomishima; Kristen J Brennand; Qisheng Zhang; Robert E Schwartz; Todd Evans; Lorenz Studer; Shuibing Chen
Journal: Cell Stem Cell Date: 2017-07-20 Impact factor: 24.633

2. A method to investigate radial glia cell behavior using two-photon time-lapse microscopy in an ex vivo model of spinal cord development.

Authors: Janelle M P Pakan; Kieran W McDermott
Journal: Front Neuroanat Date: 2014-04-10 Impact factor: 3.856

Cerebral organoids in a dish: progress and prospects.

1. An intrinsic mechanism of corticogenesis from embryonic stem cells.

2. Self-organized formation of polarized cortical tissues from ESCs and its active manipulation by extrinsic signals.

3. Neurogenic radial glia in the outer subventricular zone of human neocortex.

4. Pyramidal neurons derived from human pluripotent stem cells integrate efficiently into mouse brain circuits in vivo.

5. Next-generation regenerative medicine: organogenesis from stem cells in 3D culture.

6. Modeling human cortical development in vitro using induced pluripotent stem cells.

7. Induction of pluripotent stem cells from adult human fibroblasts by defined factors.

8. Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses.

9. Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling.

1. High-Content Screening in hPSC-Neural Progenitors Identifies Drug Candidates that Inhibit Zika Virus Infection in Fetal-like Organoids and Adult Brain.

2. A method to investigate radial glia cell behavior using two-photon time-lapse microscopy in an ex vivo model of spinal cord development.

Review 3. Three-Dimensional Models of the Human Brain Development and Diseases.

4. Genomics at cellular resolution: insights into cognitive disorders and their evolution.

Review 5. Biological and medical applications of a brain-on-a-chip.

Review 6. Stem Cells in Neurotoxicology/Developmental Neurotoxicology: Current Scenario and Future Prospects.

Review 7. Patient-Specific Organoid and Organ-on-a-Chip: 3D Cell-Culture Meets 3D Printing and Numerical Simulation.

8. Can a few non-coding mutations make a human brain?

Review 9. Understanding the molecular basis of autism in a dish using hiPSCs-derived neurons from ASD patients.

Review 10. The Application of Human iPSCs in Neurological Diseases: From Bench to Bedside.