| Literature DB >> 24065327 |
Taseera Kabanda1, Mark J Siedner, Jeffrey D Klausner, Conrad Muzoora, David R Boulware.
Abstract
The cryptococcal antigen (CRAG) lateral flow assay (LFA) had 100% sensitivity and specificity on cerebrospinal fluid samples. Pretreatment LFA titers correlated with quantitative cultures (R(2) = 0.7) and predicted 2- and 10-week mortality. The CRAG LFA is an accurate diagnostic assay for CSF and should be considered for point-of-care diagnosis of cryptococcal meningitis.Entities:
Keywords: HIV; cryptococcal meningitis; diagnosis; point-of-care; sub-Saharan Africa
Mesh:
Year: 2013 PMID: 24065327 PMCID: PMC3864499 DOI: 10.1093/cid/cit641
Source DB: PubMed Journal: Clin Infect Dis ISSN: 1058-4838 Impact factor: 9.079