| Literature DB >> 19681708 |
Somnuek Sungkanuparph1, Scott G Filler, Ploenchan Chetchotisakd, Peter G Pappas, Tracy L Nolen, Weerawat Manosuthi, Thanomsak Anekthananon, Michele I Morris, Khuanchai Supparatpinyo, Heather Kopetskie, Amy S Kendrick, Philip C Johnson, Jack D Sobel, Robert A Larsen.
Abstract
A prospective multicenter study of cryptococcal immune reconstitution inflammatory syndrome (IRIS) was conducted as a substudy of the Bacteriology and Mycology Study Group 3-01. Of 101 AIDS patients with cryptococcal meningitis who received highly active antiretroviral therapy (HAART), 13 experienced cryptococcal IRIS. No association between the timing of HAART initiation and the diagnosis of IRIS was identified. Increased baseline serum cryptococcal antigen (CrAg) titer was a risk factor for cryptococcal IRIS.Entities:
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Year: 2009 PMID: 19681708 DOI: 10.1086/605497
Source DB: PubMed Journal: Clin Infect Dis ISSN: 1058-4838 Impact factor: 9.079