BACKGROUND: There are fetuses demonstrating very large myelomeningocele lesion which can not be covered with autochothonous skin. MATERIAL AND METHODS: We use Integra™ artificial skin for intrauterine coverage of the back lesion. A reverse latissimus dorsi flap was used postnatally to reinforce the repair site. CONCLUSION: Integra™ appears to be a suitable coverage for large soft tissue defects in utero. Moreover, a postnatal reverse latissimus dorsi flap appears to markedly strengthen tissue coverage over a spinal cord rescued in utero.
BACKGROUND: There are fetuses demonstrating very large myelomeningocele lesion which can not be covered with autochothonous skin. MATERIAL AND METHODS: We use Integra™ artificial skin for intrauterine coverage of the back lesion. A reverse latissimus dorsi flap was used postnatally to reinforce the repair site. CONCLUSION: Integra™ appears to be a suitable coverage for large soft tissue defects in utero. Moreover, a postnatal reverse latissimus dorsi flap appears to markedly strengthen tissue coverage over a spinal cord rescued in utero.
Authors: Catherine A Mazzola; A Leland Albright; Leslie N Sutton; Gerald F Tuite; Ronald L Hamilton; Ian F Pollack Journal: N Engl J Med Date: 2002-07-25 Impact factor: 91.245
Authors: M Meuli; C Meuli-Simmen; G M Hutchins; C D Yingling; K M Hoffman; M R Harrison; N S Adzick Journal: Nat Med Date: 1995-04 Impact factor: 53.440
Authors: C Schiestl; K Neuhaus; T Biedermann; S Böttcher-Haberzeth; E Reichmann; M Meuli Journal: Eur J Pediatr Surg Date: 2010-12-14 Impact factor: 2.191
Authors: N Scott Adzick; Elizabeth A Thom; Catherine Y Spong; John W Brock; Pamela K Burrows; Mark P Johnson; Lori J Howell; Jody A Farrell; Mary E Dabrowiak; Leslie N Sutton; Nalin Gupta; Noel B Tulipan; Mary E D'Alton; Diana L Farmer Journal: N Engl J Med Date: 2011-02-09 Impact factor: 91.245