Literature DB >> 24051866

High frequency of false-positive hepatitis C virus enzyme-linked immunosorbent assay in Rakai, Uganda.

Caroline E Mullis1, Oliver Laeyendecker, Steven J Reynolds, Ponsiano Ocama, Jeffrey Quinn, Iga Boaz, Ronald H Gray, Gregory D Kirk, David L Thomas, Thomas C Quinn, Lara Stabinski.   

Abstract

The prevalence of hepatitis C virus (HCV) infection in sub-Saharan Africa remains unclear. We tested 1000 individuals from Rakai, Uganda, with the Ortho version 3.0 HCV enzyme-linked immunosorbent assay. All serologically positive samples were tested for HCV RNA. Seventy-six of the 1000 (7.6%) participants were HCV antibody positive; none were confirmed by detection of HCV RNA.

Entities:  

Keywords:  Africa; ELISA; hepatitis C virus

Mesh：

Substances：

Year:  2013        PMID： 24051866      PMCID： PMC3840403          DOI： 10.1093/cid/cit602

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN： 1058-4838            Impact factor:   9.079


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