Literature DB >> 24049678

Spatial Light Interference Microscopy (SLIM) using twisted-nematic liquid-crystal modulation.

Tan H Nguyen1, Gabriel Popescu.   

Abstract

We report the use of a twisted nematic liquid-crystal spatial light modulator (TNLC-SLM) for quantitative phase imaging. The experimental setup is a new implementation of the SLIM principle, which is a phase shifting, white light method for quantitative phase imaging. The approach is based on switching between the phase and amplitude modulation modes of the SLM. Our system is able to deliver a 0.99 nm spatial and 1.33 nm temporal pathlength sensitivity while retaining the optical transverse resolution. The system is implemented as an additional module mounted to a conventional microscope, which makes the system very easy to deploy and integrate with other imaging modalities.

Keywords:  (060.5060) Phase modulation; (070.6120) Spatial light modulators; (110.0110) Imaging systems; (180.0180) Microscopy; (180.3170) Interference microscopy

Year:  2013        PMID: 24049678      PMCID: PMC3771828          DOI: 10.1364/BOE.4.001571

Source DB:  PubMed          Journal:  Biomed Opt Express        ISSN: 2156-7085            Impact factor:   3.732


  24 in total

1.  Diffraction phase microscopy with white light.

Authors:  Basanta Bhaduri; Hoa Pham; Mustafa Mir; Gabriel Popescu
Journal:  Opt Lett       Date:  2012-03-15       Impact factor: 3.776

2.  Measurement of red blood cell mechanics during morphological changes.

Authors:  YongKeun Park; Catherine A Best; Kamran Badizadegan; Ramachandra R Dasari; Michael S Feld; Tatiana Kuriabova; Mark L Henle; Alex J Levine; Gabriel Popescu
Journal:  Proc Natl Acad Sci U S A       Date:  2010-03-29       Impact factor: 11.205

3.  Spectral-domain optical coherence phase microscopy for quantitative phase-contrast imaging.

Authors:  Chulmin Joo; Taner Akkin; Barry Cense; Boris H Park; Johannes F de Boer
Journal:  Opt Lett       Date:  2005-08-15       Impact factor: 3.776

4.  Tomographic phase microscopy.

Authors:  Wonshik Choi; Christopher Fang-Yen; Kamran Badizadegan; Seungeun Oh; Niyom Lue; Ramachandra R Dasari; Michael S Feld
Journal:  Nat Methods       Date:  2007-08-12       Impact factor: 28.547

5.  Quadriwave lateral shearing interferometry for quantitative phase microscopy of living cells.

Authors:  Pierre Bon; Guillaume Maucort; Benoit Wattellier; Serge Monneret
Journal:  Opt Express       Date:  2009-07-20       Impact factor: 3.894

6.  Label-free intracellular transport measured by spatial light interference microscopy.

Authors:  Zhuo Wang; Larry Millet; Vincent Chan; Huafeng Ding; Martha U Gillette; Rashid Bashir; Gabriel Popescu
Journal:  J Biomed Opt       Date:  2011-02       Impact factor: 3.170

7.  One-dimensional deterministic transport in neurons measured by dispersion-relation phase spectroscopy.

Authors:  Ru Wang; Zhuo Wang; Joe Leigh; Nahil Sobh; Larry Millet; Martha U Gillette; Alex J Levine; Gabriel Popescu
Journal:  J Phys Condens Matter       Date:  2011-08-23       Impact factor: 2.333

8.  Topography and refractometry of nanostructures using spatial light interference microscopy.

Authors:  Zhuo Wang; Ik Su Chun; Xiuling Li; Zhun-Yong Ong; Eric Pop; Larry Millet; Martha Gillette; Gabriel Popescu
Journal:  Opt Lett       Date:  2010-01-15       Impact factor: 3.776

9.  Spatial light interference tomography (SLIT).

Authors:  Zhuo Wang; Daniel L Marks; Paul Scott Carney; Larry J Millet; Martha U Gillette; Agustin Mihi; Paul V Braun; Zhen Shen; Supriya G Prasanth; Gabriel Popescu
Journal:  Opt Express       Date:  2011-10-10       Impact factor: 3.894

10.  Dynamic quantitative phase imaging for biological objects using a pixelated phase mask.

Authors:  Katherine Creath; Goldie Goldstein
Journal:  Biomed Opt Express       Date:  2012-10-17       Impact factor: 3.732

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  6 in total

1.  Introduction to the Novel Techniques in Microscopy feature issue.

Authors:  Jerome Mertz; Eric O Potma
Journal:  Biomed Opt Express       Date:  2013-09-19       Impact factor: 3.732

2.  Spatial light interference microscopy: principle and applications to biomedicine.

Authors:  Xi Chen; Mikhail E Kandel; Gabriel Popescu
Journal:  Adv Opt Photonics       Date:  2021-05-05       Impact factor: 24.750

3.  Complex spatial light modulation capability of a dual layer in-plane switching liquid crystal panel.

Authors:  Seong-Woo Jang; Wonwoo Choi; Soobin Kim; Jonghyun Lee; Sehwan Na; Sangwon Ham; Juseong Park; Hoon Kang; Byeong-Kwon Ju; Hwi Kim
Journal:  Sci Rep       Date:  2022-05-18       Impact factor: 4.996

4.  A Rapid Detection Method for Morphological Characteristics of Biological Cells Based on Phase Imaging.

Authors:  Wen-Bo Tang; Ying Ji; Ming-Ming Zhang; Zhi-Ya Chen; Yuan-Yuan Xu; Ya-Wei Wang
Journal:  Biomed Res Int       Date:  2018-04-11       Impact factor: 3.411

5.  Phase correlation imaging of unlabeled cell dynamics.

Authors:  Lihong Ma; Gannavarpu Rajshekhar; Ru Wang; Basanta Bhaduri; Shamira Sridharan; Mustafa Mir; Arindam Chakraborty; Rajashekar Iyer; Supriya Prasanth; Larry Millet; Martha U Gillette; Gabriel Popescu
Journal:  Sci Rep       Date:  2016-09-12       Impact factor: 4.379

6.  3D surface morphology imaging of opaque microstructures via light-field microscopy.

Authors:  Yong Da Sie; Chun-Yu Lin; Shean-Jen Chen
Journal:  Sci Rep       Date:  2018-07-12       Impact factor: 4.379

  6 in total

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