Ali Kemal Sivrioğlu1, Ümit Aksoy Özcan, Ali Türk, Sıla Ulus, Mehmet Erdem Yıldız, Güner Sönmez, Hakan Mutlu. 1. From the Department of Radiology (A.K.S. draksivrioglu@gmail.com), Aksaz Military Hospital, Muğla, Turkey; the Department of Radiology (Ü.A.Ö., A.T., S.U., M.E.Y.), Acıbadem University School of Medicine, İstanbul, Turkey; the Department of Radiology (G.S., H.M.), GATA Haydarpaşa Teaching Hospital, İstanbul, Turkey.
Abstract
PURPOSE: We aimed to test the null hypothesis that relative apparent diffusion coefficient (rADC) and relative signal intensity values (rSI(HASTE)) do not change in the evaluation of placental maturation with advancing gestational age. MATERIALS AND METHODS: Fifty-six fetuses with diffusion-weighted magnetic resonance imaging (DW-MRI) data were enrolled in this retrospective study. Fetuses were analyzed in three different gestational age groups: group 1, 18-23 weeks; group 2, 24-28 weeks; and group 3, 29-38 weeks. The rADC (mean ADC/ADC(globe)) and rSI(HASTE) values (mean SI(HASTE)/SI(globe)) were obtained. Two radiologists experienced in fetal MRI who were blinded to the patient information reviewed MRI images independently. Kruskal-Wallis Test was used to compare the rADC and rSI(HASTE) with gestational age groups. The agreement between the two blinded readers was tested using Krippendorff's alpha ratio. RESULTS: Both placental rADC values and placental rSI(HASTE) values were not significantly different between the gestational age groups (P = 0.688 and P = 0.280, respectively). rADC and rSI(HASTE) measurements were reproducible with a good agreement between the two readers (Krippendorff's alpha ratio was 0.613 and 0.778, respectively). CONCLUSION: The rADC and rSI(HASTE) values do not change with advancing gestational age.
PURPOSE: We aimed to test the null hypothesis that relative apparent diffusion coefficient (rADC) and relative signal intensity values (rSI(HASTE)) do not change in the evaluation of placental maturation with advancing gestational age. MATERIALS AND METHODS: Fifty-six fetuses with diffusion-weighted magnetic resonance imaging (DW-MRI) data were enrolled in this retrospective study. Fetuses were analyzed in three different gestational age groups: group 1, 18-23 weeks; group 2, 24-28 weeks; and group 3, 29-38 weeks. The rADC (mean ADC/ADC(globe)) and rSI(HASTE) values (mean SI(HASTE)/SI(globe)) were obtained. Two radiologists experienced in fetal MRI who were blinded to the patient information reviewed MRI images independently. Kruskal-Wallis Test was used to compare the rADC and rSI(HASTE) with gestational age groups. The agreement between the two blinded readers was tested using Krippendorff's alpha ratio. RESULTS: Both placental rADC values and placental rSI(HASTE) values were not significantly different between the gestational age groups (P = 0.688 and P = 0.280, respectively). rADC and rSI(HASTE) measurements were reproducible with a good agreement between the two readers (Krippendorff's alpha ratio was 0.613 and 0.778, respectively). CONCLUSION: The rADC and rSI(HASTE) values do not change with advancing gestational age.
Authors: Lana Vasung; Esra Abaci Turk; Silvina L Ferradal; Jason Sutin; Jeffrey N Stout; Banu Ahtam; Pei-Yi Lin; P Ellen Grant Journal: Neuroimage Date: 2018-07-21 Impact factor: 6.556
Authors: Eddy Solomon; Reut Avni; Ron Hadas; Tal Raz; Joel Richard Garbow; Peter Bendel; Lucio Frydman; Michal Neeman Journal: Proc Natl Acad Sci U S A Date: 2014-06-26 Impact factor: 11.205