Literature DB >> 24045713

Trichloromethyl ketones: asymmetric transfer hydrogenation and subsequent Jocic-type reactions with amines.

Michael S Perryman1, Matthew E Harris, Jade L Foster, Anushka Joshi, Guy J Clarkson, David J Fox.   

Abstract

Amino-amides are important pharmaceutical building-blocks. The enantioselective reduction of trichloromethyl ketones using ruthenium transfer hydrogenation catalysts is reported. The products react in a range of Jocic-type reactions to give enantiomerically enriched amino-amides.

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Year:  2013        PMID： 24045713     DOI： 10.1039/c3cc46070c

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  4 in total

1.  Catalytic Enantioselective Addition of an Allyl Group to Ketones Containing a Tri-, a Di-, or a Monohalomethyl Moiety. Stereochemical Control Based on Distinctive Electronic and Steric Attributes of C-Cl, C-Br, and C-F Bonds.

Authors:  Diana C Fager; KyungA Lee; Amir H Hoveyda
Journal:  J Am Chem Soc       Date:  2019-09-25       Impact factor: 15.419

2.  Transition Metal-Free N-Arylation of Amino Acid Esters with Diaryliodonium Salts.

Authors:  Gabriella Kervefors; Leonard Kersting; Berit Olofsson
Journal:  Chemistry       Date:  2021-03-03       Impact factor: 5.236

3.  Pd-catalyzed synthesis of 1-(hetero)aryl-2,2,2-trichloroethanols using chloral hydrate and (hetero)arylboroxines.

Authors:  Minori Shimizu; Yuta Okuda; Koki Toyoda; Ryo Akiyama; Hiraku Shinozaki; Tetsuya Yamamoto
Journal:  RSC Adv       Date:  2021-05-18       Impact factor: 3.361

4.  Pyrrole-Based Conjugated Microporous Polymers as Efficient Heterogeneous Catalysts for Knoevenagel Condensation.

Authors:  Ruidong Gao; Guang Zhang; Fanli Lu; Long Chen; Yang Li
Journal:  Front Chem       Date:  2021-05-10       Impact factor: 5.221
  4 in total

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