Literature DB >> 24042967

Flash chemistry: flow chemistry that cannot be done in batch.

Jun-ichi Yoshida1, Yusuke Takahashi, Aiichiro Nagaki.   

Abstract

Flash chemistry based on high-resolution reaction time control using flow microreactors enables chemical reactions that cannot be done in batch and serves as a powerful tool for laboratory synthesis of organic compounds and for production in chemical and pharmaceutical industries.

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Year:  2013        PMID： 24042967     DOI： 10.1039/c3cc44709j

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  28 in total

1.  A fully automated flow-based approach for accelerated peptide synthesis.

Authors:  Alexander J Mijalis; Dale A Thomas; Mark D Simon; Andrea Adamo; Ryan Beaumont; Klavs F Jensen; Bradley L Pentelute
Journal:  Nat Chem Biol       Date:  2017-02-28       Impact factor: 15.040

Review 2.  Expanding the medicinal chemistry synthetic toolbox.

Authors:  Jonas Boström; Dean G Brown; Robert J Young; György M Keserü
Journal:  Nat Rev Drug Discov       Date:  2018-08-24       Impact factor: 84.694

Review 3.  Heterogeneous photocatalysis in flow chemical reactors.

Authors:  Christopher G Thomson; Ai-Lan Lee; Filipe Vilela
Journal:  Beilstein J Org Chem       Date:  2020-06-26       Impact factor: 2.883

4.  The assembly and use of continuous flow systems for chemical synthesis.

Authors:  Joshua Britton; Timothy F Jamison
Journal:  Nat Protoc       Date:  2017-10-26       Impact factor: 13.491

Review 5.  Automating drug discovery.

Authors:  Gisbert Schneider
Journal:  Nat Rev Drug Discov       Date:  2017-12-15       Impact factor: 84.694

Review 6.  Continuous Flow Technology as an Enabler for Innovative Transformations Exploiting Carbenes, Nitrenes, and Benzynes.

Authors:  Kian Donnelly; Marcus Baumann
Journal:  J Org Chem       Date:  2022-06-14       Impact factor: 4.198

7.  Fully automated fast-flow synthesis of antisense phosphorodiamidate morpholino oligomers.

Authors:  Chengxi Li; Alex J Callahan; Mark D Simon; Kyle A Totaro; Alexander J Mijalis; Kruttika-Suhas Phadke; Genwei Zhang; Nina Hartrampf; Carly K Schissel; Ming Zhou; Hong Zong; Gunnar J Hanson; Andrei Loas; Nicola L B Pohl; David E Verhoeven; Bradley L Pentelute
Journal:  Nat Commun       Date:  2021-07-20       Impact factor: 14.919

8.  3D-Printed Labware for High-Throughput Immobilization of Enzymes.

Authors:  Michael B Spano; Brandan H Tran; Sudipta Majumdar; Gregory A Weiss
Journal:  J Org Chem       Date:  2020-06-17       Impact factor: 4.198

Review 9.  The synthesis of active pharmaceutical ingredients (APIs) using continuous flow chemistry.

Authors:  Marcus Baumann; Ian R Baxendale
Journal:  Beilstein J Org Chem       Date:  2015-07-17       Impact factor: 2.883

Review 10.  Strategic Application of Residence-Time Control in Continuous-Flow Reactors.

Authors:  István M Mándity; Sándor B Ötvös; Ferenc Fülöp
Journal:  ChemistryOpen       Date:  2015-05-20       Impact factor: 2.911
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