Literature DB >> 24038751

Rapid removal of matrices from small-volume samples by step-voltage nanoelectrospray.

Zhenwei Wei1, Shuo Han, Xiaoyun Gong, Yaoyao Zhao, Chengdui Yang, Sichun Zhang, Xinrong Zhang.   

Abstract

Matrix unloaded: By changing from fixed-voltage (left) to step-voltage nanoelectrospray (right), the mass-spectrometric analysis of small-volume physiological samples is possible. Separation and ionization are achieved in one process, which avoids sample loss and dilution and prevents interference by the matrix. The result is high sensitivity even for samples at the nanoliter level.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  analytical methods; electromigration; mass spectrometry; matrix interference; matrix removal

Year:  2013        PMID： 24038751     DOI： 10.1002/anie.201302870

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  4 in total

1.  Direct Mass Spectrometry Analysis of Complex Mixtures by Nanoelectrospray with Simultaneous Atmospheric Pressure Chemical Ionization and Electrophoretic Separation Capabilities.

Authors:  Dmytro S Kulyk; Devin J Swiner; Taghi Sahraeian; Abraham K Badu-Tawiah
Journal:  Anal Chem       Date:  2019-09-06       Impact factor: 6.986

2.  Facile Improvement of Negative Ion Mode Electrospray Ionization Using Capillary Vibrating Sharp-Edge Spray Ionization.

Authors:  Chong Li; Kushani Attanayake; Stephen J Valentine; Peng Li
Journal:  Anal Chem       Date:  2020-01-15       Impact factor: 6.986

3.  DNA methylation as a potential diagnosis indicator for rapid discrimination of rare cancer cells and normal cells.

Authors:  Xingyu Si; Yaoyao Zhao; Chengdui Yang; Sichun Zhang; Xinrong Zhang
Journal:  Sci Rep       Date:  2015-07-03       Impact factor: 4.379

4.  Nanosecond photochemically promoted click chemistry for enhanced neuropeptide visualization and rapid protein labeling.

Authors:  Gongyu Li; Fengfei Ma; Qinjingwen Cao; Zhen Zheng; Kellen DeLaney; Rui Liu; Lingjun Li
Journal:  Nat Commun       Date:  2019-10-16       Impact factor: 14.919
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.