OBJECTIVES: The aims of this study were to assess antimicrobial resistance in Neisseria gonorrhoeae infections and update the treatment in the national guidelines for the syndromic management of sexually transmitted infections in Morocco. METHODS: 171 men complaining of urethral discharge were recruited from basic health services during 2009. Urethral swab samples were collected and N gonorrhoeae identification was performed by culture. Antimicrobial susceptibility testing was performed using the Etest method and the antimicrobial agents tested were ciprofloxacin, penicillin, spectinomycin, tetracycline, ceftriaxone and cefixime. RESULTS: A total of 72 isolates were examined. Significant resistance to tetracycline (92.8%) and ciprofloxacin (86.8%), which was used as first-line treatment in gonococcal infections, was noted. No resistance to spectinomycin, ceftriaxone or cefixime was detected in all the isolates. CONCLUSIONS: Following these results the Ministry of Health of Morocco replaced ciprofloxacin and introduced ceftriaxone 250 mg as a single dose in the treatment of gonococcal infections. Using funds from the Global Fund to Fight AIDS, Tuberculosis and Malaria (the Global Fund), a surveillance programme was set up for antimicrobial resistance testing in N gonorrhoeae.
OBJECTIVES: The aims of this study were to assess antimicrobial resistance in Neisseria gonorrhoeae infections and update the treatment in the national guidelines for the syndromic management of sexually transmitted infections in Morocco. METHODS: 171 men complaining of urethral discharge were recruited from basic health services during 2009. Urethral swab samples were collected and N gonorrhoeae identification was performed by culture. Antimicrobial susceptibility testing was performed using the Etest method and the antimicrobial agents tested were ciprofloxacin, penicillin, spectinomycin, tetracycline, ceftriaxone and cefixime. RESULTS: A total of 72 isolates were examined. Significant resistance to tetracycline (92.8%) and ciprofloxacin (86.8%), which was used as first-line treatment in gonococcal infections, was noted. No resistance to spectinomycin, ceftriaxone or cefixime was detected in all the isolates. CONCLUSIONS: Following these results the Ministry of Health of Morocco replaced ciprofloxacin and introduced ceftriaxone 250 mg as a single dose in the treatment of gonococcal infections. Using funds from the Global Fund to Fight AIDS, Tuberculosis and Malaria (the Global Fund), a surveillance programme was set up for antimicrobial resistance testing in N gonorrhoeae.
Authors: Aziza Bennani; Amina El-Kettani; Amina Hançali; Houssine El-Rhilani; Kamal Alami; Mohamed Youbi; Jane Rowley; Laith Abu-Raddad; Alex Smolak; Melanie Taylor; Guy Mahiané; John Stover; Eline L Korenromp Journal: PLoS One Date: 2017-08-24 Impact factor: 3.240
Authors: Eline L Korenromp; Guy Mahiané; Jane Rowley; Nico Nagelkerke; Laith Abu-Raddad; Francis Ndowa; Amina El-Kettani; Houssine El-Rhilani; Philippe Mayaud; R Matthew Chico; Carel Pretorius; Kendall Hecht; Teodora Wi Journal: Sex Transm Infect Date: 2017-03-21 Impact factor: 3.519
Authors: Nicholas A Medland; Ye Zhang; Praveena Gunaratnam; David A Lewis; Basil Donovan; David M Whiley; Rebecca J Guy; John M Kaldor Journal: Euro Surveill Date: 2022-05