Literature DB >> 2403642

Transcription of the promoter of the rat NF-1 gene depends on the integrity of an Sp1 recognition site.

R Ammendola1, F Gounari, G Piaggio, V De Simone, R Cortese.   

Abstract

The transcription start site and promoter of the rat gene coding for the transcription factor NF-1 have been identified. The NF-1 promoter was fused to the chloramphenicol acetyltransferase-coding sequence, and the resulting plasmid was transcriptionally active in the HepG2 cell line. Footprinting and gel retardation analysis indicated that the transcription factor Sp1 binds to the NF-1 promoter. Mutants in the Sp1-binding site displayed a strong reduction in transcriptional activity.

Entities:  

Mesh：

Substances：

Year:  1990        PMID： 2403642      PMCID： PMC360762          DOI： 10.1128/mcb.10.1.387-390.1990

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  20 in total

1.  Transcripts of the Drosophila blastoderm-specific locus, terminus, are concentrated posteriorly and encode a potential DNA-binding finger.

Authors:  R M Baldarelli; P A Mahoney; F Salas; E Gustavson; P D Boyer; M F Chang; M Roark; J A Lengyel
Journal:  Dev Biol       Date:  1988-01       Impact factor: 3.582

2.  Sequences upstream from the mouse c-mos oncogene may function as a transcription termination signal.

Authors:  M L McGeady; T G Wood; J V Maizel; G F Vande Woude
Journal:  DNA       Date:  1986-08

3.  Determinants of rat albumin promoter tissue specificity analyzed by an improved transient expression system.

Authors:  J M Heard; P Herbomel; M O Ott; A Mottura-Rollier; M Weiss; M Yaniv
Journal:  Mol Cell Biol       Date:  1987-07       Impact factor: 4.272

4.  Affinity purification of sequence-specific DNA binding proteins.

Authors:  J T Kadonaga; R Tjian
Journal:  Proc Natl Acad Sci U S A       Date:  1986-08       Impact factor: 11.205

Review 5.  Homeo boxes in the study of development.

Authors:  W J Gehring
Journal:  Science       Date:  1987-06-05       Impact factor: 47.728

6.  Synergistic activation and repression of transcription by Drosophila homeobox proteins.

Authors:  K Han; M S Levine; J L Manley
Journal:  Cell       Date:  1989-02-24       Impact factor: 41.582

7.  Firefly luciferase gene: structure and expression in mammalian cells.

Authors:  J R de Wet; K V Wood; M DeLuca; D R Helinski; S Subramani
Journal:  Mol Cell Biol       Date:  1987-02       Impact factor: 4.272

8.  Negative control of liver-specific gene expression: cloned human retinol-binding protein gene is repressed in HeLa cells.

Authors:  V Colantuoni; A Pirozzi; C Blance; R Cortese
Journal:  EMBO J       Date:  1987-03       Impact factor: 11.598

9.  Cis- and trans-acting elements responsible for the cell-specific expression of the human alpha 1-antitrypsin gene.

Authors:  V De Simone; G Ciliberto; E Hardon; G Paonessa; F Palla; L Lundberg; R Cortese
Journal:  EMBO J       Date:  1987-09       Impact factor: 11.598

10.  The human haptoglobin gene promoter: interleukin-6-responsive elements interact with a DNA-binding protein induced by interleukin-6.

Authors:  S Oliviero; R Cortese
Journal:  EMBO J       Date:  1989-04       Impact factor: 11.598
View more
  6 in total

1.  Transcription of the mouse secretory protease inhibitor p12 gene is activated by the developmentally regulated positive transcription factor Sp1.

Authors:  S Robidoux; P Gosselin; M Harvey; S Leclerc; S L Guérin
Journal:  Mol Cell Biol       Date:  1992-09       Impact factor: 4.272

2.  Mouse BTEB3, a new member of the basic transcription element binding protein (BTEB) family, activates expression from GC-rich minimal promoter regions.

Authors:  K M Martin; W N Cooper; J C Metcalfe; P R Kemp
Journal:  Biochem J       Date:  2000-02-01       Impact factor: 3.857

3.  Analysis of proteins binding to the proximal promoter region of the human cytomegalovirus IE-1/2 enhancer/promoter reveals both consensus and aberrant recognition sequences for transcription factors Sp1 and CREB.

Authors:  D Lang; H Fickenscher; T Stamminger
Journal:  Nucleic Acids Res       Date:  1992-07-11       Impact factor: 16.971

4.  Sp1 is essential and its position is important for p120 gene transcription: a 35 bp juxtaposed positive regulatory element enhances transcription 2.5 fold.

Authors:  M A Haidar; D Henning; H Busch
Journal:  Nucleic Acids Res       Date:  1991-12-11       Impact factor: 16.971

Review 5.  Noncoding control region of naturally occurring BK virus variants: sequence comparison and functional analysis.

Authors:  U Moens; T Johansen; J I Johnsen; O M Seternes; T Traavik
Journal:  Virus Genes       Date:  1995       Impact factor: 2.332

6.  Two regulatory proteins that bind to the basic transcription element (BTE), a GC box sequence in the promoter region of the rat P-4501A1 gene.

Authors:  H Imataka; K Sogawa; K Yasumoto; Y Kikuchi; K Sasano; A Kobayashi; M Hayami; Y Fujii-Kuriyama
Journal:  EMBO J       Date:  1992-10       Impact factor: 11.598
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.