Literature DB >> 2403533

Differences in microbicidal activities of human macrophages against Toxoplasma gondii and Trypanosoma cruzi.

D M Israelski1, F G Araujo, J S Wachtel, L Heinrichs, J S Remington.   

Abstract

The microbicidal activities of normal human pelvic macrophages against infection by the intracellular protozoa Toxoplasma gondii and Trypanosoma cruzi were examined. Macrophages allowed infection by T. gondii and yet possessed remarkable microbicidal activity against this organism. In contrast, human macrophages were not microbicidal against T. cruzi.

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Year:  1990        PMID： 2403533      PMCID： PMC258441          DOI： 10.1128/iai.58.1.263-265.1990

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  7 in total

1.  Connective tissue reactions in normal and immunized mice to a reticulotropic strain of Trypanosoma cruzi.

Authors:  W H TALIAFERRO; T PIZZI
Journal:  J Infect Dis       Date:  1955 May-Jun       Impact factor: 5.226

2.  Nonoxidative microbicidal activity in normal human alveolar and peritoneal macrophages.

Authors:  J R Catterall; C M Black; J P Leventhal; N W Rizk; J S Wachtel; J S Remington
Journal:  Infect Immun       Date:  1987-07       Impact factor: 3.441

3.  Activation of tissue macrophages from AIDS patients: in vitro response of AIDS alveolar macrophages to lymphokines and interferon-gamma.

Authors:  H W Murray; R A Gellene; D M Libby; C D Rothermel; B Y Rubin
Journal:  J Immunol       Date:  1985-10       Impact factor: 5.422

4.  Trypanosoma cruzi: induction of microbicidal activity in human mononuclear phagocytes.

Authors:  N Nogueira; S Chaplan; M Reesink; J Tydings; Z A Cohn
Journal:  J Immunol       Date:  1982-05       Impact factor: 5.422

5.  Oxygen-independent killing by alveolar macrophages.

Authors:  J R Catterall; S D Sharma; J S Remington
Journal:  J Exp Med       Date:  1986-05-01       Impact factor: 14.307

6.  Effect of normal and activated human macrophages on Toxoplasma gondii.

Authors:  S E Anderson; J S Remington
Journal:  J Exp Med       Date:  1974-05-01       Impact factor: 14.307

7.  Failure to trigger the oxidative metabolic burst by normal macrophages: possible mechanism for survival of intracellular pathogens.

Authors:  C B Wilson; V Tsai; J S Remington
Journal:  J Exp Med       Date:  1980-02-01       Impact factor: 14.307
  7 in total
  3 in total

1.  Down-regulation of MHC class II molecules and inability to up-regulate class I molecules in murine macrophages after infection with Toxoplasma gondii.

Authors:  C G Lüder; T Lang; B Beuerle; U Gross
Journal:  Clin Exp Immunol       Date:  1998-05       Impact factor: 4.330

2.  Infection of murine macrophages with Toxoplasma gondii is associated with release of transforming growth factor beta and downregulation of expression of tumor necrosis factor receptors.

Authors:  L E Bermudez; G Covaro; J Remington
Journal:  Infect Immun       Date:  1993-10       Impact factor: 3.441

3.  Remarkable in vitro and in vivo activities of the hydroxynaphthoquinone 566C80 against tachyzoites and tissue cysts of Toxoplasma gondii.

Authors:  F G Araujo; J Huskinson; J S Remington
Journal:  Antimicrob Agents Chemother       Date:  1991-02       Impact factor: 5.191
  3 in total

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