Literature DB >> 24030671

Minimally invasive aortic valve replacement with Perceval valves: first clinical experience.

Giuseppe Santarpino1, Steffen Pfeiffer, Joachim Sirch, Ferdinand Vogt, Giovanni Concistrè, Theodor Fischlein.   

Abstract

AIM: Although minimally invasive aortic valve replacement (MIAVR) has been shown to cause less morbidity than conventional surgery, it has not yet received broad application. The purpose of this study was to evaluate sutureless implantation using the Perceval S aortic valve bioprosthesis (Sorin Group, Saluggia, Italy) via ministernotomy.
METHODS: Seventy-two patients (43 women, 29 men; mean age 77.4 ± 5.3 years) with isolated aortic valve stenosis (mean gradient of 52 ± 14 mmHg) underwent aortic valve implantation with the sutureless Perceval S bioprosthesis, following cardiopulmonary bypass (CPB), aortic cross-clamping (ACC), cardioplegic arrest and removal of the calcified native valve. The mean logistic EuroSCORE was 9.7 ± 6.2%.
RESULTS: The prosthetic valve was successfully deployed in all patients. Thirty-day mortality was 1.4% (n = 1). Mean CBP, ACC, and implantation times were 68 ± 18, 40 ± 13 and 8.9 ± 4 min, respectively. Perioperative echocardiography revealed significant paravalvular leakage in one patient. Postoperative mean gradient was 11.6 ± 5.1 mmHg. At a mean follow-up of 13 ± 6.7 months, no significant paravalvular leakage or valvular regurgitation was observed, and no migration or dislodgement of the prosthesis occurred.
CONCLUSION: This study shows that sutureless implantation of the Perceval S aortic valve bioprosthesis provides a simple and reproducible alternative for MIAVR. As the valve does not need to be sutured, it may also result in reduced ACC and CPB times. This self-anchoring valve may also allow the application of MIAVR to a broader spectrum of patients. This new technology needs a long-term follow-up.

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Year:  2014        PMID: 24030671     DOI: 10.2459/JCM.0b013e328360936a

Source DB:  PubMed          Journal:  J Cardiovasc Med (Hagerstown)        ISSN: 1558-2027            Impact factor:   2.160


  2 in total

Review 1.  Aortic valve replacement through J-shaped partial upper sternotomy.

Authors:  Shahzad G Raja; Umberto Benedetto; Mohamed Amrani
Journal:  J Thorac Dis       Date:  2013-11       Impact factor: 2.895

2.  Experimental Study and Early Clinical Application Of a Sutureless Aortic Bioprosthesis.

Authors:  Walter J Gomes; João Carlos Leal; Fabio Biscegli Jatene; Nelson A Hossne; Renata Gabaldi; Glaucia Basso Frazzato; Guilherme Agreli; Domingo M Braile
Journal:  Braz J Cardiovasc Surg       Date:  2015 Sep-Oct
  2 in total

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