Literature DB >> 24030469

Interactions between age and moderate alcohol effects on simulated driving performance.

Alfredo L Sklar1, Jeff Boissoneault, Mark T Fillmore, Sara Jo Nixon.   

Abstract

RATIONALE: There is a substantial body of literature documenting the deleterious effects of both alcohol consumption and age on driving performance. There is, however, limited work examining the interaction of age and acute alcohol consumption.
OBJECTIVES: The current study was conducted to determine if moderate alcohol doses differentially affect the driving performance of older and younger adults.
METHODS: Healthy older (55-70) and younger (25-35) adults were tested during a baseline session and again following consumption of one of three beverages [0.0 % (placebo), 0.04 % or 0.065 % target breath alcohol concentration]. Measures of driving precision and average speed were recorded.
RESULTS: Older adults performed more poorly on precision driving measures and drove more slowly than younger adults at baseline. After controlling for baseline performance, interactions between alcohol and age were observed following beverage consumption on two measures of driving precision with older adults exhibiting greater impairment as a result of alcohol consumption.
CONCLUSIONS: These data provide evidence that older adults may be more susceptible to the effects of alcohol on certain measures of driving performance. An investigation of mechanisms accounting for alcohol's effects on driving in older and younger adults is required. Further evaluation using more complex driving environments is needed to assess the real-world implication of this interaction.

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Year:  2013        PMID: 24030469      PMCID: PMC3947134          DOI: 10.1007/s00213-013-3269-4

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN: 0033-3158            Impact factor:   4.530


  37 in total

1.  The effects of age and alcohol intoxication on simulated driving performance, awareness and self-restraint.

Authors:  W C Quillian; D J Cox; B P Kovatchev; C Phillips
Journal:  Age Ageing       Date:  1999-01       Impact factor: 10.668

2.  Effects of alcohol on risk-taking during simulated driving.

Authors:  Scott E Burian; Anthony Liguori; John H Robinson
Journal:  Hum Psychopharmacol       Date:  2002-04       Impact factor: 1.672

3.  Fast, but error-prone, responses during acute alcohol intoxication: effects of stimulus-response mapping complexity.

Authors:  Tom A Schweizer; Pierre Jolicoeur; M Vogel-Sprott; Mike J Dixon
Journal:  Alcohol Clin Exp Res       Date:  2004-04       Impact factor: 3.455

4.  Predictive validity of driving-simulator assessments following traumatic brain injury: a preliminary study.

Authors:  Henry L Lew; John H Poole; Eun Ha Lee; David L Jaffe; Hsiu-Chen Huang; Edward Brodd
Journal:  Brain Inj       Date:  2005-03       Impact factor: 2.311

5.  Are bad drivers more impaired by alcohol? Sober driving precision predicts impairment from alcohol in a simulated driving task.

Authors:  Emily L R Harrison; Mark T Fillmore
Journal:  Accid Anal Prev       Date:  2005-09

6.  Prediction of blood alcohol concentrations in human subjects. Updating the Widmark Equation.

Authors:  P E Watson; I D Watson; R D Batt
Journal:  J Stud Alcohol       Date:  1981-07

7.  Effect of low and moderate doses of alcohol on driving hazard perception latency and driving speed.

Authors:  R West; J Wilding; D French; R Kemp; A Irving
Journal:  Addiction       Date:  1993-04       Impact factor: 6.526

8.  Behavioral impairment under alcohol: cognitive and pharmacokinetic factors.

Authors:  M T Fillmore; M Vogel-Sprott
Journal:  Alcohol Clin Exp Res       Date:  1998-10       Impact factor: 3.455

9.  Alcohol pharmacodynamics in young-elderly adults contrasted with young and middle-aged subjects.

Authors:  L A Tupler; S Hege; E H Ellinwood
Journal:  Psychopharmacology (Berl)       Date:  1995-04       Impact factor: 4.530

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  10 in total

Review 1.  Age-related effects of alcohol from adolescent, adult, and aged populations using human and animal models.

Authors:  Lindsay M Squeglia; Jeff Boissoneault; Candice E Van Skike; Sara Jo Nixon; Douglas B Matthews
Journal:  Alcohol Clin Exp Res       Date:  2014-08-25       Impact factor: 3.455

2.  Effects of Age and Acute Moderate Alcohol Consumption on Electrophysiological Indices of Attention.

Authors:  Christian C Garcia; Ben Lewis; Jeff Boissoneault; Sara Jo Nixon
Journal:  J Stud Alcohol Drugs       Date:  2020-05       Impact factor: 2.582

3.  Working Memory Performance Following Acute Alcohol: Replication and Extension of Dose by Age Interactions.

Authors:  Ben Lewis; Christian C Garcia; Jeff Boissoneault; Julianne L Price; Sara Jo Nixon
Journal:  J Stud Alcohol Drugs       Date:  2019-01       Impact factor: 2.582

4.  Acute alcohol exposure dose-dependently alleviates social avoidance in adolescent mice and inhibits social investigation in adult mice.

Authors:  Joel S Raymond; Bianca B Wilson; Oliver Tan; Anand Gururajan; Michael T Bowen
Journal:  Psychopharmacology (Berl)       Date:  2019-07-25       Impact factor: 4.530

5.  Effects of Age and Acute Moderate Alcohol Administration on Neurophysiology During Simulated Driving.

Authors:  Ben Lewis; Jeff Boissoneault; Ian Frazier; Sara Jo Nixon
Journal:  Alcohol Clin Exp Res       Date:  2016-10-14       Impact factor: 3.455

6.  Effects of acute alcohol and driving complexity in older and younger adults.

Authors:  Julianne L Price; Ben Lewis; Jeff Boissoneault; Ian R Frazier; Sara Jo Nixon
Journal:  Psychopharmacology (Berl)       Date:  2017-12-06       Impact factor: 4.530

7.  The effects of acute alcohol on psychomotor, set-shifting, and working memory performance in older men and women.

Authors:  Lauren A Hoffman; Alfredo L Sklar; Sara Jo Nixon
Journal:  Alcohol       Date:  2015-03-02       Impact factor: 2.405

8.  Alcohol Doesn't Always Compromise Cognitive Function: Exploring Moderate Doses in Young Adults.

Authors:  Laurena Hoffman; Sara Jo Nixon
Journal:  J Stud Alcohol Drugs       Date:  2015-11       Impact factor: 2.582

9.  Acute Tolerance to the Analgesic Effects of Alcohol.

Authors:  Michelle K Williams; Darya Vitus; Erin Ferguson; Bethany Stennett; Michael Robinson; Jeff Boissoneault
Journal:  J Stud Alcohol Drugs       Date:  2021-05       Impact factor: 2.582

Review 10.  Alcohol consumption for simulated driving performance: A systematic review.

Authors:  Mohammad Saeid Rezaee-Zavareh; Payman Salamati; Mahdi Ramezani-Binabaj; Mina Saeidnejad; Mansoureh Rousta; Farhad Shokraneh; Vafa Rahimi-Movaghar
Journal:  Chin J Traumatol       Date:  2017-04-14
  10 in total

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