Literature DB >> 24029100

Spinal gout: a great mimicker. A case report and literature review.

I Ahmad1, J G Tejada.   

Abstract

Spinal gout is not as rare as was previously thought and mimics heterogeneous spinal conditions such as rheumatoid, septic, seronegative arthropathies and primary or secondary neoplasms. Imaging findings are nonspecific and usually manifest late. In clinical settings, suspicious for spinal gout, needle biopsy may help for further characterization. A 57-year-old man with no significant past medical history presented in the emergency department with severe non radiating low back pain of one week duration. His laboratory tests were significant for uric acid of 642 μmol/L, erythrocyte sedimentation rate 93 mm/hour, and C-reactive protein 8.3 mg/dl. The lumbar spine MRI showed nonspecific acute inflammatory extensive lumbar facet arthropathy and soft tissue enhancement. The radiological and clinical information was insufficient to differentiate among septic arthritis, rheumatoid arthritis, seronegative arthropathy or gout. A lumbar facet fluoroscopy-fluoroscopic CT-guided needle biopsy was performed. The biopsy demonstrated negative birefringent crystals consistent with gout. Although the spinal gout is not rare, few case reports describe the role of needle biopsy and mimics. We present a comparative review of limited reports addressing the role of needle biopsy in mimics of spinal gout.

Entities:  

Year:  2012        PMID: 24029100     DOI: 10.1177/197140091202500518

Source DB:  PubMed          Journal:  Neuroradiol J        ISSN: 1971-4009


  5 in total

1.  Tophaceous gout of the cervical and thoracic spine with concomitant epidural infection.

Authors:  Christina W Cheng; Quynh T Nguyen; Haitao Zhou
Journal:  AME Case Rep       Date:  2018-07-10

2.  Mimicking Meningismus: A Case of Atlantoaxial Gout.

Authors:  Johnathon Gorman; Andrew Van Der Westhuizen; Sadia Raheez Qamar; Clark Funnell
Journal:  Neurol Clin Pract       Date:  2021-06

Review 3.  Gout in the Spine: Imaging, Diagnosis, and Outcomes.

Authors:  Michael Toprover; Svetlana Krasnokutsky; Michael H Pillinger
Journal:  Curr Rheumatol Rep       Date:  2015-12       Impact factor: 4.592

Review 4.  Gout: An old disease in new perspective - A review.

Authors:  Gaafar Ragab; Mohsen Elshahaly; Thomas Bardin
Journal:  J Adv Res       Date:  2017-05-10       Impact factor: 10.479

5.  Gout Storm.

Authors:  Danilo Martins; Carolina Rodrigues Tonon; Rafael Lopes Pacca; Natanye Lemes Matchil; Luiz Antonio Jorge Junior; Dênis Silva Queiroz; Filipe Welson Leal Pereira; Alana Maia Silva; Vinicius Padovese; Marcelo Padovani de Toledo Moraes; Daniel Luiz da Silva; Vinicius Cardoso Nóbrega; Emilio Carlos Curcelli; Marina Politi Okoshi
Journal:  Am J Case Rep       Date:  2021-09-20
  5 in total

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