Literature DB >> 30264031

Tophaceous gout of the cervical and thoracic spine with concomitant epidural infection.

Christina W Cheng1, Quynh T Nguyen1,2, Haitao Zhou1.   

Abstract

Tophaceous gout of the spine is an underappreciated source of back pain in patients with or without neurological decline. It has been reported to occur in the cervical, thoracic and lumbar spine. Rarely, does it occur at more than one region of the spine. Advanced imaging with magnetic resonance imaging and computed tomography are usually not helpful in differentiating between infection, malignancy and gout. Clinician should have a high suspicion of spinal gout in patients with history of gout who presents with renal insufficiency, presence of peripheral tophi on exam, with elevated serum uric acid and creatinine levels, erythrocyte sedimentation rate and C-reactive protein. Here we present a case of a 23-year-old male with history of gout and chronic renal disease with progressive weakness in his lower extremities with new urinary incontinence who was found to have spinal gout with epidural infection of both the cervical and thoracic spine. Our patient was successfully managed with surgical decompression followed by medical treatment with antibiotics and steroids.

Entities:  

Keywords:  Spine; chronic kidney disease; epidural infection; spinal gout; tophaceous gout

Year:  2018        PMID: 30264031      PMCID: PMC6155567          DOI: 10.21037/acr.2018.07.01

Source DB:  PubMed          Journal:  AME Case Rep        ISSN: 2523-1995


  30 in total

1.  Detection of lumbar facet joint gouty arthritis using dual-energy computed tomography.

Authors:  Pragnesh Parikh; Ronald Butendieck; Mark Kransdorf; Kenneth Calamia
Journal:  J Rheumatol       Date:  2010-10       Impact factor: 4.666

Review 2.  Tophaceous Gout of the Lumbar Spine: Case Report and Review of the Literature.

Authors:  Andrey Volkov; David L Rhoiney; Roderick Claybrooks
Journal:  Turk Neurosurg       Date:  2015       Impact factor: 1.003

Review 3.  Gouty arthropathy of the lumbar spine: a case report and review of the literature.

Authors:  J C King; C Nicholas
Journal:  Spine (Phila Pa 1976)       Date:  1997-10-01       Impact factor: 3.468

4.  Gout; an unusual case with softening and subluxation of the first cervical vertebra and splenomegaly.

Authors:  G D KERSLEY; L MANDEL; M R JEFFREY
Journal:  Ann Rheum Dis       Date:  1950-12       Impact factor: 19.103

Review 5.  Gout in the spine.

Authors:  Eduardo Massato Hasegawa; Filipe Martins de Mello; Cláudia Goldenstein-Schainberg; Ricardo Fuller
Journal:  Rev Bras Reumatol       Date:  2013 May-Jun

6.  Thoracic spinal cord compression by extradural tophus: a case report and review of the literature.

Authors:  T Liu; H Liu; T Zhu
Journal:  Spinal Cord Ser Cases       Date:  2015-10-08

Review 7.  Gout in the Spine: Imaging, Diagnosis, and Outcomes.

Authors:  Michael Toprover; Svetlana Krasnokutsky; Michael H Pillinger
Journal:  Curr Rheumatol Rep       Date:  2015-12       Impact factor: 4.592

8.  Evidence for a promoter of urate crystal formation in gouty synovial fluid.

Authors:  N W McGill; P A Dieppe
Journal:  Ann Rheum Dis       Date:  1991-08       Impact factor: 19.103

9.  Tophaceous gout of the spine causing neural compression.

Authors:  Jong-Won Yoon; Kyung-Bum Park; Hyun Park; Dong-Ho Kang; Chul-Hee Lee; Soo-Hyun Hwang; Jin-Myung Jung; Jong-Woo Han; In Sung Park
Journal:  Korean J Spine       Date:  2013-09-30

Review 10.  Thoracic cord compression due to ligamentum flavum gouty tophus: a case report and literature review.

Authors:  Z-F Zheng; H-L Shi; Y Xing; D Li; J-Y Jia; S Lin
Journal:  Spinal Cord       Date:  2015-06-16       Impact factor: 2.772

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  3 in total

Review 1.  Beyond Medical Treatment: Surgical Treatment of Gout.

Authors:  Jonathan Carcione; Shari Bodofsky; Brian LaMoreaux; Naomi Schlesinger
Journal:  Curr Rheumatol Rep       Date:  2020-11-24       Impact factor: 4.592

Review 2.  Tophaceous gout of the atlantoaxial joint: a case report.

Authors:  Andrew Benjamin Romero; Evan Paul Johnson; John S Kirkpatrick
Journal:  J Med Case Rep       Date:  2021-02-15

3.  Gout Storm.

Authors:  Danilo Martins; Carolina Rodrigues Tonon; Rafael Lopes Pacca; Natanye Lemes Matchil; Luiz Antonio Jorge Junior; Dênis Silva Queiroz; Filipe Welson Leal Pereira; Alana Maia Silva; Vinicius Padovese; Marcelo Padovani de Toledo Moraes; Daniel Luiz da Silva; Vinicius Cardoso Nóbrega; Emilio Carlos Curcelli; Marina Politi Okoshi
Journal:  Am J Case Rep       Date:  2021-09-20
  3 in total

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