| Literature DB >> 24028628 |
Elias Silva Dos Santos1, Leila Cristiane Virgens de Souza, Patrícia Nascimento de Assis, Paulo Fernando Almeida, Elias Ramos-de-Souza.
Abstract
The biogenic production of hydrogen sulfide gas by sulfate-reducing bacteria (SRB) causes serious economic problems for natural gas and oil industry. One of the key enzymes important in this biologic process is adenosine phosphosulfate reductase (APSr). Using virtual screening technique we have discovered 15 compounds that are novel potential APSr inhibitors. Three of them have been selected for molecular docking and microbiological studies which have shown good inhibition of SRB in the produced water from the oil industry.Entities:
Keywords: SRB; inhibition APS reductase; souring
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Year: 2013 PMID： 24028628 DOI： 10.1080/07391102.2013.834850
Source DB: PubMed Journal: J Biomol Struct Dyn ISSN： 0739-1102