Literature DB >> 24014558

A novel treatment for management of a trapped placenta using intracervical nitroglycerin tablets.

Blake Conley Rodgers1, Adam Pasternak, Richard Gray.   

Abstract

A 34-year-old gravida 2, para 1 woman delivered a viable male infant and developed retained placenta due to entrapment. A nitroglycerin tablet was used to relax the lower uterine segment and cervix, which allowed the placenta to pass through the cervix for delivery. The nitroglycerin tablet was placed in the cervix and held in place by the delivering physician as it dissolved. Soon after administration, the intact placenta delivered. The patient did not experience the typical side effects of headache, asymptomatic decrease in blood pressure, hypotension, palpitations or dizziness that can be associated with administration of nitroglycerin. We suspect that this novel localised route of nitroglycerin administration may be an effective management strategy to treat trapped placenta while minimising side effects. However, the outcomes of this treatment would require further study.

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Year:  2013        PMID: 24014558      PMCID: PMC3794125          DOI: 10.1136/bcr-2013-010505

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  10 in total

1.  A randomized controlled trial comparing oxytocin administration before and after placental delivery in the prevention of postpartum hemorrhage.

Authors:  K W Jackson; J R Allbert; G K Schemmer; M Elliot; A Humphrey; J Taylor
Journal:  Am J Obstet Gynecol       Date:  2001-10       Impact factor: 8.661

2.  Prolonged third stage of labor: morbidity and risk factors.

Authors:  C A Combs; R K Laros
Journal:  Obstet Gynecol       Date:  1991-06       Impact factor: 7.661

3.  Sublingual nitroglycerin seems to be effective in the management of retained placenta.

Authors:  Erling Ekerhovd; Maria Bullarbo
Journal:  Acta Obstet Gynecol Scand       Date:  2008       Impact factor: 3.636

4.  The retained placenta.

Authors:  Andrew D Weeks
Journal:  Best Pract Res Clin Obstet Gynaecol       Date:  2008-09-14       Impact factor: 5.237

Review 5.  Tocolysis for management of retained placenta.

Authors:  Hany Abdel-Aleem; Mahmoud A Abdel-Aleem; Omar M Shaaban
Journal:  Cochrane Database Syst Rev       Date:  2011-01-19

6.  The use of intravenous nitroglycerin for emergency cervico-uterine relaxation.

Authors:  A Wessén; P Elowsson; P Axemo; B Lindberg
Journal:  Acta Anaesthesiol Scand       Date:  1995-08       Impact factor: 2.105

Review 7.  The use of intravenous nitroglycerin for cervico-uterine relaxation: a review of the literature.

Authors:  P Dufour; D Vinatier; F Puech
Journal:  Arch Gynecol Obstet       Date:  1997       Impact factor: 2.344

8.  Sublingual nitroglycerin for management of retained placenta.

Authors:  M Bullarbo; J Tjugum; E Ekerhovd
Journal:  Int J Gynaecol Obstet       Date:  2005-10-14       Impact factor: 3.561

9.  Manual removal of the placenta. Incidence and clinical significance.

Authors:  A Tandberg; S Albrechtsen; O E Iversen
Journal:  Acta Obstet Gynecol Scand       Date:  1999-01       Impact factor: 3.636

10.  Nitroglycerin for management of retained placenta: a multicenter study.

Authors:  Maria Bullarbo; Hans Bokström; Håkan Lilja; Elisabeth Almström; Nina Lassenius; Agneta Hansson; Erling Ekerhovd
Journal:  Obstet Gynecol Int       Date:  2012-05-22
  10 in total
  2 in total

1.  Retained Placenta and Postpartum Hemorrhage: A Case Report and Review of Literature.

Authors:  Lucie Sorelle Tchuinte Lekuikeu; Connie Moreland
Journal:  Cureus       Date:  2022-04-22

Review 2.  Nitroglycerin for management of retained placenta.

Authors:  Hany Abdel-Aleem; Mahmoud A Abdel-Aleem; Omar M Shaaban
Journal:  Cochrane Database Syst Rev       Date:  2015-11-12
  2 in total

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