Literature DB >> 24013329

Urodynamic studies in spinal cord tethering.

James T Kearns1, Domenic Esposito, Beverly Dooley, David Frim, Mohan S Gundeti.   

Abstract

INTRODUCTION: Tethered cord syndrome (TCS) is of particular interest to urologists through its effects on the function of the lower urinary tract. Tethering of the spinal cord can result in bladder dysfunction with multiple manifestations, clinically raging from urinary retention and detrusor under-activity to urinary incontinence, over-activity of the detrusor, and sphincter dysfunction. Goals of management include protecting renal function and preserving patient quality of life.
METHODS: Evaluation of a TCS patient with urinary complaints begins with a thorough history and physical examination. Further characterization of urinary symptoms with a voiding diary provides vital information that helps to direct treatment while engaging the patient and family in the treatment plan. Urodynamic studies then provide key diagnostic data regarding bladder function, bladder outlet resistance, and urinary sphincter function. In the pediatric population, particular care must be paid to counseling patients and their families prior to the procedure to alleviate the often-considerable anxiety associated with an invasive procedure.
CONCLUSION: The armamentarium for management of neurogenic bladder associated with TCS includes behavioral training, biofeedback therapy, medications, patient-performed procedures, and surgical intervention. The choice of intervention depends on the patient's symptoms, urodynamic findings, and patient and family preferences. The primary problem of TCS should be addressed first through detethering, and then the urological team can use progressively more aggressive therapies as necessary. Interpretation and treatment by a dedicated, specialized, multidisciplinary team that includes the pediatric urologist, pediatric neurosurgeon and dedicated nurse practitioner, is critical for successful treatment.

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Year:  2013        PMID: 24013329     DOI: 10.1007/s00381-013-2136-2

Source DB:  PubMed          Journal:  Childs Nerv Syst        ISSN: 0256-7040            Impact factor:   1.475


  14 in total

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5.  Continence outcomes in patients undergoing robotic assisted laparoscopic mitrofanoff appendicovesicostomy.

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6.  Paediatric robotic-assisted laparoscopic augmentation ileocystoplasty and Mitrofanoff appendicovesicostomy (RALIMA): feasibility of and initial experience with the University of Chicago technique.

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Journal:  BJU Int       Date:  2010-10-13       Impact factor: 5.588

7.  Natural fill urodynamics and conventional cystometrogram in infants with neurogenic bladder.

Authors:  Bettina Jorgensen; Lars Henning Olsen; Troels Munch Jorgensen
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Review 8.  Latest technologic and surgical developments in using InterStim Therapy for sacral neuromodulation: impact on treatment success and safety.

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9.  Randomized double-blind, active-controlled phase 3 study to assess 12-month safety and efficacy of mirabegron, a β(3)-adrenoceptor agonist, in overactive bladder.

Authors:  Christopher R Chapple; Steven A Kaplan; David Mitcheson; Jiri Klecka; Jana Cummings; Ted Drogendijk; Caroline Dorrepaal; Nancy Martin
Journal:  Eur Urol       Date:  2012-11-06       Impact factor: 20.096

10.  Neurogenic bladder.

Authors:  Peter T Dorsher; Peter M McIntosh
Journal:  Adv Urol       Date:  2012-02-08
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Review 2.  Systematic Review of Urologic Outcomes from Tethered Cord Release in Occult Spinal Dysraphism in Children.

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4.  Effects of electroacupuncture combined with clean intermittent catheterization on urinary retention after spinal cord injury: a single blind randomized controlled clinical trial.

Authors:  Xu-Dong Gu; Jing Wang; Peng Yu; Jian-Hua Li; Yun-Hai Yao; Jian-Ming Fu; Zhong-Li Wang; Ming Zeng; Liang Li; Ming Shi; Wen-Ping Pan
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