Literature DB >> 24010818

Assessing HIV and AIDS treatment safety and health-related quality of life among cohort of Malaysian patients: a discussion on methodological approach.

Imran Ahmed Syed1,2, Syed Azhar Syed Sulaiman1, Mohammad Azmi Hassali1, Christopher K C Lee3.   

Abstract

BACKGROUND: Health-related quality of life (HRQoL) is increasingly recognized as an important outcome and as a complement to traditional biological end points of diseases such as mortality. Unless there is a complete cure available for HIV/AIDS, development and implementation of a reliable and valid cross cultural quality of life measure is necessary to assess not only the physical and medical needs of HIV/AIDS people, but their psychological, social, environmental, and spiritual areas of life.
METHODS: A qualitative exploration of HIV/AIDS patients' understanding, perceptions and expectations will be carried out with the help of semi structured interview guide by in depth interviews, while quantitative assessment of patient reported adverse drug reactions and their impact on health related quality of life will be carried out by using data collection tool comprising patient demographics, SF-12, Naranjo scale, and a clinical data sheet. RESULTS/OUTCOMES: The findings may serve as baseline QOL data of people living with HIV/AIDS in Malaysia and also a source data to aid construction of management plan to improve HIV/AIDS patients' QOL. It will also provide basic information about HIV/AIDS patients' perceptions, expectations and believes towards HIV/AIDS and its treatment which may help in designing strategies to enhance patients' awareness which in turn can help in addressing issues related to compliance and adherence.
© 2013 John Wiley & Sons Ltd.

Entities:  

Keywords:  HIV/AIDS; adverse drug reactions; patients' perspective; quality of life

Mesh:

Year:  2013        PMID: 24010818      PMCID: PMC5060823          DOI: 10.1111/hex.12116

Source DB:  PubMed          Journal:  Health Expect        ISSN: 1369-6513            Impact factor:   3.377


  30 in total

1.  Lipodystrophy and quality of life in HIV: symptom management issues.

Authors:  Patrice K Nicholas; Kenn M Kirksey; Inge B Corless; Jeanne Kemppainen
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2.  HIV-infected women's decisions to take antiretrovirals.

Authors:  T R Misener; R L Sowell
Journal:  West J Nurs Res       Date:  1998-08       Impact factor: 1.967

3.  "I will start treatment when I think the time is right": HIV-positive gay men talk about their decision not to access antiretroviral therapy.

Authors:  R S Gold; D T Ridge
Journal:  AIDS Care       Date:  2001-12

4.  Perceptions of HAART among gay men who declined a treatment offer: preliminary results from an interview-based study.

Authors:  V Cooper; D Buick; R Horne; N Lambert; G Gellaitry; H Leake; M Fisher
Journal:  AIDS Care       Date:  2002-06

5.  Gender differences in health-related quality of life in patients with HIV/AIDS.

Authors:  Joseph M Mrus; Paige L Williams; Joel Tsevat; Susan E Cohn; Albert W Wu
Journal:  Qual Life Res       Date:  2005-03       Impact factor: 4.147

6.  Gender and age differences in quality of life and the impact of psychopathological symptoms among HIV-infected patients.

Authors:  Marco Pereira; Maria Cristina Canavarro
Journal:  AIDS Behav       Date:  2011-11

7.  Survival and quality of life among HIV-positive people on antiretroviral therapy in Cambodia.

Authors:  Guy Morineau; Mean Chhi Vun; Hubert Barennes; Robert Cameron Wolf; Ngak Song; Dimitri Prybylski; Natpratan Chawalit
Journal:  AIDS Patient Care STDS       Date:  2009-08       Impact factor: 5.078

8.  Health-related quality of life and patient-provider relationships in HIV-infected patients during the first three years after starting PI-containing antiretroviral treatment.

Authors:  M Préau; C Leport; D Salmon-Ceron; P Carrieri; H Portier; G Chene; B Spire; P Choutet; F Raffi; M Morin
Journal:  AIDS Care       Date:  2004-07

9.  Sexual dysfunction in HIV-infected men: role of antiretroviral therapy, hypogonadism and lipodystrophy.

Authors:  Giovanni Guaraldi; Kety Luzi; Rita Murri; Antonio Granata; Maria De Paola; Gabriella Orlando; Nicola Squillace; Davide Malmusi; Cesare Carani; Dante Comelli; Roberto Esposito; Esteban Martinez
Journal:  Antivir Ther       Date:  2007

10.  Assessment of quality of life in HAART-treated HIV-positive subjects with body fat redistribution in Rwanda.

Authors:  Eugene Mutimura; Aimee Stewart; Nigel J Crowther
Journal:  AIDS Res Ther       Date:  2007-09-18       Impact factor: 2.250

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