Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 A new RING tossed into an old HAT.

Literature DB >> 24010705

A new RING tossed into an old HAT.

Abstract

p300 and CBP are multi-domain histone acetyltransferases (HATs) that regulate gene expression and are mutated in human diseases including cancer. Delvecchio and colleagues report the structure of the p300 catalytic core, revealing the presence of a previously unknown RING domain that regulates the enzyme's activity.

Entities: Chemical Disease Gene Mutation Species

Mesh：

Substances：

Year: 2013 PMID： 24010705 PMCID： PMC3836368 DOI： 10.1016/j.str.2013.08.011

Source DB: PubMed Journal: Structure ISSN： 0969-2126 Impact factor: 5.006

13 in total

Review 1. Histone acetylation: a switch between repressive and permissive chromatin. Second in review series on chromatin dynamics.

Authors: Anton Eberharter; Peter B Becker
Journal: EMBO Rep Date: 2002-03 Impact factor: 8.807

Review 2. Histone acetyltransferase complexes: one size doesn't fit all.

Authors: Kenneth K Lee; Jerry L Workman
Journal: Nat Rev Mol Cell Biol Date: 2007-04 Impact factor: 94.444

Review 3. RING domain E3 ubiquitin ligases.

Authors: Raymond J Deshaies; Claudio A P Joazeiro
Journal: Annu Rev Biochem Date: 2009 Impact factor: 23.643

4. Structure of the p300 catalytic core and implications for chromatin targeting and HAT regulation.

Authors: Manuela Delvecchio; Jonathan Gaucher; Carmen Aguilar-Gurrieri; Esther Ortega; Daniel Panne
Journal: Nat Struct Mol Biol Date: 2013-08-11 Impact factor: 15.369

5. Histone modifiers in cancer: friends or foes?

Authors: Idan Cohen; Elżbieta Poręba; Kinga Kamieniarz; Robert Schneider
Journal: Genes Cancer Date: 2011-06

Review 6. Catalysis and substrate selection by histone/protein lysine acetyltransferases.

Authors: Christopher E Berndsen; John M Denu
Journal: Curr Opin Struct Biol Date: 2008-12 Impact factor: 6.809

Review 7. CBP and p300: HATs for different occasions.

Authors: Eric Kalkhoven
Journal: Biochem Pharmacol Date: 2004-09-15 Impact factor: 5.858

8. Regulation of the p300 HAT domain via a novel activation loop.

Authors: Paul R Thompson; Dongxia Wang; Ling Wang; Marcella Fulco; Natalia Pediconi; Dianzheng Zhang; Woojin An; Qingyuan Ge; Robert G Roeder; Jiemin Wong; Massimo Levrero; Vittorio Sartorelli; Robert J Cotter; Philip A Cole
Journal: Nat Struct Mol Biol Date: 2004-03-07 Impact factor: 15.369

Review 9. p300/CBP and cancer.

Authors: Narayanan Gopalakrishna Iyer; Hilal Ozdag; Carlos Caldas
Journal: Oncogene Date: 2004-05-24 Impact factor: 9.867

10. Inactivating mutations of acetyltransferase genes in B-cell lymphoma.

Authors: Laura Pasqualucci; David Dominguez-Sola; Annalisa Chiarenza; Giulia Fabbri; Adina Grunn; Vladimir Trifonov; Lawryn H Kasper; Stephanie Lerach; Hongyan Tang; Jing Ma; Davide Rossi; Amy Chadburn; Vundavalli V Murty; Charles G Mullighan; Gianluca Gaidano; Raul Rabadan; Paul K Brindle; Riccardo Dalla-Favera
Journal: Nature Date: 2011-03-10 Impact factor: 49.962

2 in total

Review 1. Roles of Grainyhead-like transcription factors in cancer.

Authors: S M Frisch; J C Farris; P M Pifer
Journal: Oncogene Date: 2017-07-17 Impact factor: 9.867

2. Grainyhead-like 2 inhibits the coactivator p300, suppressing tubulogenesis and the epithelial-mesenchymal transition.

Authors: Phillip M Pifer; Joshua C Farris; Alyssa L Thomas; Peter Stoilov; James Denvir; David M Smith; Steven M Frisch
Journal: Mol Biol Cell Date: 2016-06-01 Impact factor: 4.138

2 in total