BACKGROUND: Sjögren's syndrome is an autoimmune syndrome involving the exocrine glands specially the salivary and lacrimal glands leading to xerostomia and xerophtalmia. This paper presents a case with primary Sjögren's syndrome that severe dental caries were the first clinical manifestation. CASE PRESENTATION: A 42-year-old man was referred to the School of Dentistry, Tehran University of Medical Sciences due to unexplained severe dental decays. After systematic evaluation and consultation with the rheumatologist and the ophthalmologist, the diagnosis of primary Sjögren's syndrome was suggested and confirmed by serologic and histopathologic study. CONCLUSION: Primary Sjögren's syndrome should be considered in the differential diagnosis of patients with early severe dental caries.
BACKGROUND: Sjögren's syndrome is an autoimmune syndrome involving the exocrine glands specially the salivary and lacrimal glands leading to xerostomia and xerophtalmia. This paper presents a case with primary Sjögren's syndrome that severe dental caries were the first clinical manifestation. CASE PRESENTATION: A 42-year-old man was referred to the School of Dentistry, Tehran University of Medical Sciences due to unexplained severe dental decays. After systematic evaluation and consultation with the rheumatologist and the ophthalmologist, the diagnosis of primary Sjögren's syndrome was suggested and confirmed by serologic and histopathologic study. CONCLUSION: Primary Sjögren's syndrome should be considered in the differential diagnosis of patients with early severe dental caries.
Authors: Silke Appel; Stephanie Le Hellard; Ove Bruland; Johan G Brun; Roald Omdal; Gudlaug Kristjansdottir; Elke Theander; Gunnel Nordmark; Marika Kvarnström; Per Eriksson; Lars Rönnblom; Marie Wahren-Herlenius; Roland Jonsson Journal: Ann Rheum Dis Date: 2011-03-30 Impact factor: 19.103
Authors: Roland Jonsson; Petra Vogelsang; Roman Volchenkov; Alexander Espinosa; Marie Wahren-Herlenius; Silke Appel Journal: Immunol Lett Date: 2011-07-12 Impact factor: 3.685