A review and update of Sjögren's syndrome: manifestations, diagnosis, and treatment.

Sjögren's syndrome is an autoimmune disorder that affects approximately 1% of the population. It is a disease that in recent years has not been studied extensively, but for which much study is needed. Diagnosis of this disease is extremely difficult. Until recently no strong consensus on diagnostic criteria has been published. The disease can cause dry eyes, dry mouth, vasculitis, and neurologic disease, and each symptom may be at times correctly attributed to Sjögren's or incorrectly attributed to another disease. Because it affects many different areas, many specialists (rheumatologists, primary care physicians, ophthalmologists, and dentists) have to be educated about Sjögren's syndrome's pathogenesis, manifestations, diagnosis, and treatments to manage this disease and help improve these patients' quality of life.