Literature DB >> 24007868

Six-year pilot study on nucleic acid testing for blood donations in China.

Xianlin Ye1, Baocheng Yang, Weigang Zhu, Xin Zheng, Peng Du, Jingfeng Zeng, Chengyao Li.   

Abstract

A six-year pilot study on nucleic acid testing for HBV, HCV and HIV-1 has been undertaken on sero-negative plasmas in mini-pool and individual donation testing at Shenzhen Blood Center. Of 307,740 sero-negative blood samples, 95 of 102 HBV DNA yields were confirmed positive, 80/95 (84.2%) were classified as occult HBV infection (OBI) and 15 (15.8%) as window period cases. Amongst OBIs, 45% carried anti-HBc only, 41.3% anti-HBc and anti-HBs and 13.7% anti-HBs only. HBV DNA yield was 1:3239. One HCV WP and one HIV-1 infected donations were detected. High residual risk was found in current blood donations screening in China.
Copyright © 2013 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Blood donors; Blood safety; Nucleic acid testing; Viruses

Mesh：

Substances：

Year:  2013        PMID： 24007868     DOI： 10.1016/j.transci.2013.08.005

Source DB:  PubMed          Journal:  Transfus Apher Sci        ISSN： 1473-0502            Impact factor:   1.764


  9 in total

1.  Characterisation and follow-up study of occult hepatitis B virus infection in anti-HBc-positive qualified blood donors in southern China.

Authors:  Xianlin Ye; Tong Li; Xiaoxuan Xu; Peng Du; Jinfeng Zeng; Weigang Zhu; Baocheng Yang; Chengyao Li; Jean-Pierre Allain
Journal:  Blood Transfus       Date:  2016-05-17       Impact factor: 3.443

2.  High-Frequency Notable HBV Mutations Identified in Blood Donors With Occult Hepatitis B Infection From Heyuan City of Southern China.

Authors:  Xianlin Ye; Lihua Liu; Lina Chen; Xianghui Nie; Lu Huang; Denghuang Ye; Jinfeng Zeng; Tong Li; Bin Li; Min Xu; Limin Chen
Journal:  Front Immunol       Date:  2022-05-13       Impact factor: 8.786

3.  Prevalence of hepatitis B surface antigen (HBsAg) in a blood donor population born prior to and after implementation of universal HBV vaccination in Shenzhen, China.

Authors:  Zhen Wang; Jinfeng Zeng; Tingting Li; Xin Zheng; Xiaoxuan Xu; Xianlin Ye; Liang Lu; Weigang Zhu; Baocheng Yang; Jean-Pierre Allain; Chengyao Li
Journal:  BMC Infect Dis       Date:  2016-09-20       Impact factor: 3.090

4.  Prevalence of HBV DNA among 20 million seronegative blood donations in China from 2010 to 2015.

Authors:  Chao Liu; Le Chang; Huimin Ji; Fei Guo; Kuo Zhang; Guigao Lin; Rui Zhang; Jinming Li; Lunan Wang
Journal:  Sci Rep       Date:  2016-11-11       Impact factor: 4.379

5.  Detection of Brucellae in peripheral blood mononuclear cells for monitoring therapeutic efficacy of brucellosis infection.

Authors:  Heng Yang; Guoxia Zhang; Peifang Luo; Zuoping He; Feihuan Hu; Linhai Li; Jean-Pierre Allain; Chengyao Li; Wenjing Wang
Journal:  Antimicrob Resist Infect Control       Date:  2019-10-15       Impact factor: 4.887

6.  Molecular characteristics of HBV infection among blood donors tested HBsAg reactive in a single ELISA test in southern China.

Authors:  Xianlin Ye; Tong Li; Ran Li; Heng Liu; Junpeng Zhao; Jinfeng Zeng
Journal:  BMC Infect Dis       Date:  2021-01-19       Impact factor: 3.090

7.  High Frequency Occult Hepatitis B Virus Infection Detected in Non-Resolved Donations Suggests the Requirement of Anti-HBc Test in Blood Donors in Southern China.

Authors:  Xianlin Ye; Yu Zhao; Ran Li; Tong Li; Xin Zheng; Wen Xiong; Jinfeng Zeng; Min Xu; Limin Chen
Journal:  Front Immunol       Date:  2021-07-28       Impact factor: 7.561

8.  The Investigation of HBV Pre-S/S Gene Mutations in Occult HBV Infected Blood Donors with anti-HBs Positive.

Authors:  Yan Guo; Yu Lan; Yuanyuan Jing; Bin Cai; Hanshi Gong; Yixin Zhang; Yong Duan
Journal:  Can J Infect Dis Med Microbiol       Date:  2022-07-19       Impact factor: 2.585

9.  The impact of nucleic acid testing to detect human immunodeficiency virus, hepatitis C virus, and hepatitis B virus yields from a single blood center in China with 10-years review.

Authors:  Danxiao Wu; Fangjun Feng; Xiaojuan Wang; Dairong Wang; Yiqin Hu; Yang Yu; Jihong Huang; Min Wang; Jie Dong; Yaling Wu; Hong Zhu; Faming Zhu
Journal:  BMC Infect Dis       Date:  2022-03-23       Impact factor: 3.090
  9 in total

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