Literature DB >> 23999753

Regulation of central nervous system autoimmunity by the aryl hydrocarbon receptor.

Francisco J Quintana1.   

Abstract

The ligand-activated transcription factor aryl hydrocarbon receptor controls the activity of several components of the immune system, many of which play an important role in neuroinflammation. This review discusses the role of AhR in T cells and dendritic cells, its relevance for the control of autoimmunity in the central nervous system, and its potential as a therapeutic target for immune-mediated disorders.

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Year:  2013        PMID： 23999753      PMCID： PMC3819215          DOI： 10.1007/s00281-013-0397-1

Source DB:  PubMed          Journal:  Semin Immunopathol        ISSN： 1863-2297            Impact factor:   9.623


  107 in total

1.  CNS myeloid DCs presenting endogenous myelin peptides 'preferentially' polarize CD4+ T(H)-17 cells in relapsing EAE.

Authors:  Samantha L Bailey; Bettina Schreiner; Eileen J McMahon; Stephen D Miller
Journal:  Nat Immunol       Date:  2007-01-07       Impact factor: 25.606

2.  Dioxin receptor is a ligand-dependent E3 ubiquitin ligase.

Authors:  Fumiaki Ohtake; Atsushi Baba; Ichiro Takada; Maiko Okada; Kei Iwasaki; Hiromi Miki; Sayuri Takahashi; Alexander Kouzmenko; Keiko Nohara; Tomoki Chiba; Yoshiaki Fujii-Kuriyama; Shigeaki Kato
Journal:  Nature       Date:  2007-03-29       Impact factor: 49.962

Review 3.  Type 1 regulatory T cells (Tr1) in autoimmunity.

Authors:  Caroline Pot; Lionel Apetoh; Vijay K Kuchroo
Journal:  Semin Immunol       Date:  2011-08-12       Impact factor: 11.130

Review 4.  The role of retinoic acid in tolerance and immunity.

Authors:  Jason A Hall; John R Grainger; Sean P Spencer; Yasmine Belkaid
Journal:  Immunity       Date:  2011-07-22       Impact factor: 31.745

5.  Alterations in CD46-mediated Tr1 regulatory T cells in patients with multiple sclerosis.

Authors:  Anne L Astier; Gregory Meiffren; Samuel Freeman; David A Hafler
Journal:  J Clin Invest       Date:  2006-11-09       Impact factor: 14.808

6.  Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation.

Authors:  Arian Laurence; Cristina M Tato; Todd S Davidson; Yuka Kanno; Zhi Chen; Zhengju Yao; Rebecca B Blank; Françoise Meylan; Richard Siegel; Lothar Hennighausen; Ethan M Shevach; John J O'shea
Journal:  Immunity       Date:  2007-03       Impact factor: 31.745

7.  In vivo induction of Tr1 cells via mucosal dendritic cells and AHR signaling.

Authors:  Henry Yim Wu; Francisco J Quintana; Andre Pires da Cunha; Benjamin T Dake; Thomas Koeglsperger; Sarah C Starossom; Howard L Weiner
Journal:  PLoS One       Date:  2011-08-23       Impact factor: 3.240

8.  Activation of aryl hydrocarbon receptor (AhR) leads to reciprocal epigenetic regulation of FoxP3 and IL-17 expression and amelioration of experimental colitis.

Authors:  Narendra P Singh; Udai P Singh; Balwan Singh; Robert L Price; Mitzi Nagarkatti; Prakash S Nagarkatti
Journal:  PLoS One       Date:  2011-08-15       Impact factor: 3.240

9.  Integration of genome-wide computation DRE search, AhR ChIP-chip and gene expression analyses of TCDD-elicited responses in the mouse liver.

Authors:  Edward Dere; Raymond Lo; Trine Celius; Jason Matthews; Timothy R Zacharewski
Journal:  BMC Genomics       Date:  2011-07-15       Impact factor: 3.969

10.  Lactobacillus bulgaricus OLL1181 activates the aryl hydrocarbon receptor pathway and inhibits colitis.

Authors:  Takeyuki Takamura; Daisuke Harama; Suguru Fukumoto; Yuki Nakamura; Naomi Shimokawa; Kayoko Ishimaru; Shuji Ikegami; Seiya Makino; Masanori Kitamura; Atsuhito Nakao
Journal:  Immunol Cell Biol       Date:  2011-02-15       Impact factor: 5.126
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  11 in total

Review 1.  Control of immune-mediated pathology via the aryl hydrocarbon receptor.

Authors:  Michael A Wheeler; Veit Rothhammer; Francisco J Quintana
Journal:  J Biol Chem       Date:  2017-06-14       Impact factor: 5.157

Review 2.  Epigenetic mechanisms underlying the pathogenesis of neurogenetic diseases.

Authors:  Irfan A Qureshi; Mark F Mehler
Journal:  Neurotherapeutics       Date:  2014-10       Impact factor: 7.620

3.  Distinct Gene Regulatory Pathways for Human Innate versus Adaptive Lymphoid Cells.

Authors:  Olivia I Koues; Patrick L Collins; Marina Cella; Michelle L Robinette; Sofia I Porter; Sarah C Pyfrom; Jacqueline E Payton; Marco Colonna; Eugene M Oltz
Journal:  Cell       Date:  2016-05-05       Impact factor: 41.582

Review 4.  Aryl Hydrocarbon Receptor in Oxidative Stress as a Double Agent and Its Biological and Therapeutic Significance.

Authors:  Alevtina Y Grishanova; Maria L Perepechaeva
Journal:  Int J Mol Sci       Date:  2022-06-16       Impact factor: 6.208

5.  Laquinimod arrests experimental autoimmune encephalomyelitis by activating the aryl hydrocarbon receptor.

Authors:  Joel Kaye; Victor Piryatinsky; Tal Birnberg; Tal Hingaly; Emanuel Raymond; Rina Kashi; Einat Amit-Romach; Ignacio S Caballero; Fadi Towfic; Mark A Ator; Efrat Rubinstein; Daphna Laifenfeld; Aric Orbach; Doron Shinar; Yael Marantz; Iris Grossman; Volker Knappertz; Michael R Hayden; Ralph Laufer
Journal:  Proc Natl Acad Sci U S A       Date:  2016-09-26       Impact factor: 11.205

Review 6.  Role and therapeutic value of dendritic cells in central nervous system autoimmunity.

Authors:  F J Quintana; A Yeste; I D Mascanfroni
Journal:  Cell Death Differ       Date:  2014-08-29       Impact factor: 15.828

7.  Expression of the neuroprotective protein aryl hydrocarbon receptor nuclear translocator 2 correlates with neuronal stress and disability in models of multiple sclerosis.

Authors:  Tissa Rahim; Pierre Becquart; Maria-Elizabeth Baeva; Jacqueline Quandt
Journal:  J Neuroinflammation       Date:  2018-09-19       Impact factor: 8.322

Review 8.  The Role of the Aryl Hydrocarbon Receptor (AHR) in Immune and Inflammatory Diseases.

Authors:  Drew R Neavin; Duan Liu; Balmiki Ray; Richard M Weinshilboum
Journal:  Int J Mol Sci       Date:  2018-12-03       Impact factor: 5.923

9.  Smoking induces DNA methylation changes in Multiple Sclerosis patients with exposure-response relationship.

Authors:  Francesco Marabita; Malin Almgren; Louise K Sjöholm; Lara Kular; Yun Liu; Tojo James; Nimrod B Kiss; Andrew P Feinberg; Tomas Olsson; Ingrid Kockum; Lars Alfredsson; Tomas J Ekström; Maja Jagodic
Journal:  Sci Rep       Date:  2017-11-06       Impact factor: 4.379

Review 10.  The aryl hydrocarbon receptor in liver inflammation.

Authors:  Antonella Carambia; Fenja Amrei Schuran
Journal:  Semin Immunopathol       Date:  2021-06-01       Impact factor: 9.623
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