PURPOSE: Despite an increasing interest in the relationships among multiple symptoms and quality of life (QOL), little known about the association between anxiety, depression, and pain and both disease-specific and generic QOL in patients with chronic obstructive pulmonary disease (COPD). METHODS: In a cross-sectional study of 100 COPD patients, disease-specific QOL was measured by St. George's Respiratory Questionnaire and generic QOL by the QOL scale. Anxiety and depression were evaluated using the Hospital Anxiety and Depression Scale, and pain was assessed with a numeric rating scale. RESULTS: Of the 100 patients, 31 % reported clinically meaningful anxiety, 13 % depression, and 45 % reported the presence of pain. Younger patients (p = 0.02) and those with higher anxiety scores (p = 0.02) reported worse disease-specific QOL. Patients with lower physical function (p = 0.04) and those with higher depression scores (p < 0.001) reported worse generic QOL. Age, comorbidity, physical function, anxiety, depression, and pain explained 19.2 and 49.6 % of the variance in disease-specific and generic QOL scores, respectively. CONCLUSIONS: Findings from this study suggest that the relationships between patient characteristics and common symptoms and QOL differ when disease-specific and generic measures of QOL are evaluated. Additional research is warranted to confirm these findings in COPD patients. Clinicians need to evaluate these common symptoms when planning and implementing symptoms management interventions to improve COPD patients' QOL.
PURPOSE: Despite an increasing interest in the relationships among multiple symptoms and quality of life (QOL), little known about the association between anxiety, depression, and pain and both disease-specific and generic QOL in patients with chronic obstructive pulmonary disease (COPD). METHODS: In a cross-sectional study of 100 COPDpatients, disease-specific QOL was measured by St. George's Respiratory Questionnaire and generic QOL by the QOL scale. Anxiety and depression were evaluated using the Hospital Anxiety and Depression Scale, and pain was assessed with a numeric rating scale. RESULTS: Of the 100 patients, 31 % reported clinically meaningful anxiety, 13 % depression, and 45 % reported the presence of pain. Younger patients (p = 0.02) and those with higher anxiety scores (p = 0.02) reported worse disease-specific QOL. Patients with lower physical function (p = 0.04) and those with higher depression scores (p < 0.001) reported worse generic QOL. Age, comorbidity, physical function, anxiety, depression, and pain explained 19.2 and 49.6 % of the variance in disease-specific and generic QOL scores, respectively. CONCLUSIONS: Findings from this study suggest that the relationships between patient characteristics and common symptoms and QOL differ when disease-specific and generic measures of QOL are evaluated. Additional research is warranted to confirm these findings in COPDpatients. Clinicians need to evaluate these common symptoms when planning and implementing symptoms management interventions to improve COPDpatients' QOL.
Authors: Craig D Blinderman; Peter Homel; J Andrew Billings; Sharon Tennstedt; Russell K Portenoy Journal: J Pain Symptom Manage Date: 2009-02-20 Impact factor: 3.612
Authors: Marc Miravitlles; Alicia Huerta; Manuel Valle; Patricia García-Sidro; Carles Forné; Carlos Crespo; José Luis López-Campos Journal: Int J Chron Obstruct Pulmon Dis Date: 2015-02-16
Authors: Vivi L Christensen; Tone Rustøen; Bruce A Cooper; Christine Miaskowski; Anne H Henriksen; Signe B Bentsen; Are M Holm Journal: Int J Chron Obstruct Pulmon Dis Date: 2016-08-02
Authors: Signe B Bentsen; Christine Miaskowski; Bruce A Cooper; Vivi L Christensen; Anne H Henriksen; Are M Holm; Tone Rustøen Journal: Int J Chron Obstruct Pulmon Dis Date: 2018-03-06
Authors: Mark Small; Victoria Higgins; Adam Lees; Nicola Johns; Anthony Mastrangelo; Tara Nazareth; Stuart J Turner Journal: COPD Date: 2015 Impact factor: 2.409