| Literature DB >> 23999616 |
Bradley T French1, Aaron F Straight.
Abstract
Faithful genome segregation depends on the functions of the eukaryotic centromere, which is characterized by the histone variant CENP-A. Gene replacement in human cells and fission yeast has now been used to show how CENP-A biochemically encodes centromere identity, as well as reveal an unexpected role for CENP-B in centromere function.Entities:
Mesh:
Substances:
Year: 2013 PMID: 23999616 DOI: 10.1038/ncb2833
Source DB: PubMed Journal: Nat Cell Biol ISSN: 1465-7392 Impact factor: 28.824