Literature DB >> 2399464

NKR-P1, a signal transduction molecule on natural killer cells.

R Giorda1, W A Rudert, C Vavassori, W H Chambers, J C Hiserodt, M Trucco.   

Abstract

Natural killer (NK) cells are a subpopulation of large granular lymphocytes characterized by densely staining azurophilic granules. NK cells are able to recognize and lyse various virally infected or neoplastic target cells without previous sensitization or major histocompatibility complex restriction. A 60-kD disulfide-linked dimer, highly expressed on NK cells, was found capable of mediating transmembrane signaling. The gene encoding this signal transduction molecule was cloned and its nucleotide sequence determined. The encoded protein showed significant homology with a number of lectin-related membrane proteins that share receptor characteristics. This protein may function as a receptor able to selectively trigger NK cell activity.

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Year:  1990        PMID： 2399464     DOI： 10.1126/science.2399464

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  53 in total

1.  Ablation of a specific cell population by the replacement of a uniquely expressed gene with a toxin gene.

Authors:  K Arase; K Saijo; H Watanabe; A Konno; H Arase; T Saito
Journal:  Proc Natl Acad Sci U S A       Date:  1999-08-03       Impact factor: 11.205

2.  On the cell biology of pit cells, the liver-specific NK cells.

Authors:  Dian-Zhong Luo; David Vermijlen; Bulent Ahishali; Vasilis Triantis; Georgia Plakoutsi; Filip Braet; Karin Vanderkerken; Eddie Wisse
Journal:  World J Gastroenterol       Date:  2000-02       Impact factor: 5.742

3.  Finding Balance: T cell Regulatory Receptor Expression during Aging.

Authors:  Mary M Cavanagh; Qian Qi; Cornelia M Weyand; Jörg J Goronzy
Journal:  Aging Dis       Date:  2011-10-28       Impact factor: 6.745

4.  Full length beta chain cDNAs of DQw9 and DQw8 molecules encode proteins that differ only at amino acid 57.

Authors:  R Giorda; E Turco; M Trucco
Journal:  Immunogenetics       Date:  1991       Impact factor: 2.846

Review 5.  NKR-P1 biology: from prototype to missing self.

Authors:  Aruz Mesci; Belma Ljutic; Andrew P Makrigiannis; James R Carlyle
Journal:  Immunol Res       Date:  2006       Impact factor: 2.829

6.  Astragaloside IV suppresses post-ischemic natural killer cell infiltration and activation in the brain: involvement of histone deacetylase inhibition.

Authors:  Baokai Dou; Shichun Li; Luyao Wei; Lixin Wang; Shiguo Zhu; Zhengtao Wang; Zunji Ke; Kaixian Chen; Zhifei Wang
Journal:  Front Med       Date:  2020-12-28       Impact factor: 4.592

7.  Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment.

Authors:  Kiran Nistala; Stuart Adams; Helen Cambrook; Simona Ursu; Biagio Olivito; Wilco de Jager; Jamie G Evans; Rolando Cimaz; Mona Bajaj-Elliott; Lucy R Wedderburn
Journal:  Proc Natl Acad Sci U S A       Date:  2010-08-02       Impact factor: 11.205

8.  Intra- and extrahepatic leukocytes and cytokine mRNA expression during liver regeneration after partial hepatectomy in rats.

Authors:  Y Sato; O Farges; D Buffello; H Bismuth
Journal:  Dig Dis Sci       Date:  1999-04       Impact factor: 3.199

9.  Lectin-like oxidized LDL receptor-1 is a cell-adhesion molecule involved in endotoxin-induced inflammation.

Authors:  Megumi Honjo; Kayo Nakamura; Kenji Yamashiro; Junichi Kiryu; Hidenobu Tanihara; Leslie M McEvoy; Yoshihito Honda; Eugene C Butcher; Tomoh Masaki; Tatsuya Sawamura
Journal:  Proc Natl Acad Sci U S A       Date:  2003-01-21       Impact factor: 11.205

10.  An autosomal dominant locus, Nka, mapping to the Ly-49 region of a rat natural killer (NK) gene complex, controls NK cell lysis of allogeneic lymphocytes.

Authors:  E Dissen; J C Ryan; W E Seaman; S Fossum
Journal:  J Exp Med       Date:  1996-05-01       Impact factor: 14.307
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