INTRODUCTION: Either deceased or living-related renal transplantation constitutes the best therapeutic option for patients with end-stage renal disease. In this retrospective study, an attempt to identify parameters that affect allograft survival in living donor renal transplantation was made. METHODS: Between January 2000 and July 2012, 478 adult patients received a renal transplant from a living-related donor in our center and their records were retrospectively reviewed in November 2012. Data concerning donor age, recipient age, donor/recipient age difference, donor/recipient gender, and ABO compatibility/incompatibility were recorded and associated with renal allograft survival rate. RESULTS: Renal allograft survival rate was 96%, 89.5%, and 77.7% in the first, fifth, and 10th yr after transplantation, respectively. Only the difference between donor and recipient age was statistically significant in relation to graft survival. In cases with age difference >13 yr, graft survival rate was lower from the third yr onward. CONCLUSIONS: Only the age difference between donor and recipient exerts an adverse impact on graft outcome after living donor renal transplantation, whereas donor age, recipient age, donor/recipient gender, and ABO incompatibility do not significantly influence renal allograft survival.
INTRODUCTION: Either deceased or living-related renal transplantation constitutes the best therapeutic option for patients with end-stage renal disease. In this retrospective study, an attempt to identify parameters that affect allograft survival in living donor renal transplantation was made. METHODS: Between January 2000 and July 2012, 478 adult patients received a renal transplant from a living-related donor in our center and their records were retrospectively reviewed in November 2012. Data concerning donor age, recipient age, donor/recipient age difference, donor/recipient gender, and ABO compatibility/incompatibility were recorded and associated with renal allograft survival rate. RESULTS: Renal allograft survival rate was 96%, 89.5%, and 77.7% in the first, fifth, and 10th yr after transplantation, respectively. Only the difference between donor and recipient age was statistically significant in relation to graft survival. In cases with age difference >13 yr, graft survival rate was lower from the third yr onward. CONCLUSIONS: Only the age difference between donor and recipient exerts an adverse impact on graft outcome after living donor renal transplantation, whereas donor age, recipient age, donor/recipient gender, and ABO incompatibility do not significantly influence renal allograft survival.
Authors: Arpita Basu; Mikel Prieto; Catherine Kosberg; Martin L Mai; Hasan A Khamash; Caroline C Jadlowiec; Naim S Issa; Patrick G Dean; Elizabeth C Lorenz; Mark D Stegall; Carrie A Schinstock Journal: Transplantation Date: 2020-06 Impact factor: 5.385
Authors: James I Kim; Ryan T Stott; Julie Soohoo; Kang Mi Lee; Gaoping Zhao; Heidi Yeh; Shaoping Deng; James F Markmann Journal: PLoS One Date: 2013-12-10 Impact factor: 3.240
Authors: Giovanni Pallotti; Gabriele Donati; Irene Capelli; Olga Baraldi; Giorgia Comai; Patrizia Agati; Michele Nichelatti; Giuseppe Cianciolo; Gaetano La Manna Journal: Comput Math Methods Med Date: 2015-12-31 Impact factor: 2.238
Authors: Rosângela Maria Gomes; Wallace Breno Barbosa; Brian Godman; Juliana de Oliveira Costa; Nélio Gomes Ribeiro Junior; Charles Simão Filho; Mariângela Leal Cherchiglia; Francisco de Assis Acurcio; Augusto Afonso Guerra Júnior Journal: Int J Environ Res Public Health Date: 2020-03-17 Impact factor: 3.390