Literature DB >> 23983320

Flavonoids from Sudanese Albizia zygia (Leguminosae, subfamily Mimosoideae), a plant with antimalarial potency.

Muna Ali Abdalla1, Hartmut Laatsch.   

Abstract

Three flavonoids were isolated for the first time from the Sudanese medicinal plants Albizia zygia. Compounds 1-3 were identified by interpretation of ESI mass data, (1)H, (13)C and 2D NMR as well as by comparison with published data as 4',7-dihydroxyflavanone (1) 3',4',7-trihydroxyflavone (2), 3-O-methylfisetin (3',4',7-trihydroxy-3-methoxyflavone, 3). All flavonoids were tested against Plasmodium falciparum, and only compound 2 showed high antimalarial activity (IC50 0.078 µg/ml).

Entities:  

Keywords:  Albizia zygia; Mimosoideae; antimalarial activity; flavonoids

Mesh：

Substances：

Year:  2011        PMID： 23983320      PMCID： PMC3746526          DOI： 10.4314/ajtcam.v9i1.8

Source DB:  PubMed          Journal:  Afr J Tradit Complement Altern Med        ISSN： 2505-0044


  8 in total

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  7 in total

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