Literature DB >> 23979275

Improving mortality following emergent surgery in older patients requires focus on complication rescue.

Kyle H Sheetz1, Seth A Waits, Robert W Krell, Darrell A Campbell, Michael J Englesbe, Amir A Ghaferi.   

Abstract

OBJECTIVE: To determine whether a hospital's ability to rescue patients from major complications underlies variation in outcomes for elderly patients undergoing emergent surgery.
BACKGROUND: Perioperative mortality rates in elderly patients undergoing emergent general/vascular operations are high and vary widely across Michigan hospitals.
METHODS: We identified 23,224 patients undergoing emergent general/vascular surgical procedures at 41 hospitals within the Michigan Surgical Quality Collaborative between 2006 and 2011. Hospitals were ranked by risk- and reliability-adjusted 30-day mortality rates and grouped into tertiles. We stratified patients by age (<75 and ≥75 years). Risk-adjusted major complication and failure-to-rescue (ie, mortality after major complication) rates were determined for each tertile of hospital mortality.
RESULTS: Risk-adjusted mortality rates in elderly patients varied 2-fold across all hospitals. Complication rates correlated poorly with mortality. Failure-to-rescue rates, however, were markedly higher in high-mortality hospitals (29% lowest tertile vs 41% highest tertile; P < 0.01). When compared with younger patients, overall failure-to-rescue rates were almost 2-fold greater in the elderly (36.1% ≥75 vs 18.7% <75; P < 0.01).
CONCLUSIONS: A hospital's failure to rescue patients from major complications seems to underlie the variation in mortality rates across Michigan hospitals after emergent surgery. Although higher failure-to-rescue rates in the elderly may signify their diminished physiological reserve for surviving critical illness, the wide variation across hospitals also highlights the importance of systems aimed at the early recognition and effective management of major complications in this vulnerable population.

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Year:  2013        PMID: 23979275      PMCID: PMC4181566          DOI: 10.1097/SLA.0b013e3182a5021d

Source DB:  PubMed          Journal:  Ann Surg        ISSN: 0003-4932            Impact factor:   12.969


  19 in total

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2.  Complications, failure to rescue, and mortality with major inpatient surgery in medicare patients.

Authors:  Amir A Ghaferi; John D Birkmeyer; Justin B Dimick
Journal:  Ann Surg       Date:  2009-12       Impact factor: 12.969

3.  Variation in quality of care after emergency general surgery procedures in the elderly.

Authors:  Angela M Ingraham; Mark E Cohen; Mehul V Raval; Clifford Y Ko; Avery B Nathens
Journal:  J Am Coll Surg       Date:  2011-06       Impact factor: 6.113

4.  The creation of a geriatric trauma unit "G-60".

Authors:  Alicia J Mangram; Vanessa K Shifflette; Christopher D Mitchell; Van A Johnson; Manuel Lorenzo; Micheal S Truitt; Anuj Goel; Mark Lyons; Ernest L Dunn
Journal:  Am Surg       Date:  2011-09       Impact factor: 0.688

5.  The intensity and variation of surgical care at the end of life: a retrospective cohort study.

Authors:  Alvin C Kwok; Marcus E Semel; Stuart R Lipsitz; Angela M Bader; Amber E Barnato; Atul A Gawande; Ashish K Jha
Journal:  Lancet       Date:  2011-10-05       Impact factor: 79.321

6.  A statewide assessment of surgical site infection following colectomy: the role of oral antibiotics.

Authors:  Michael J Englesbe; Linda Brooks; James Kubus; Martin Luchtefeld; James Lynch; Anthony Senagore; John C Eggenberger; Vic Velanovich; Darrell A Campbell
Journal:  Ann Surg       Date:  2010-09       Impact factor: 12.969

7.  Hospital characteristics associated with failure to rescue from complications after pancreatectomy.

Authors:  Amir A Ghaferi; Nicholas H Osborne; John D Birkmeyer; Justin B Dimick
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8.  Frailty as a predictor of surgical outcomes in older patients.

Authors:  Martin A Makary; Dorry L Segev; Peter J Pronovost; Dora Syin; Karen Bandeen-Roche; Purvi Patel; Ryan Takenaga; Lara Devgan; Christine G Holzmueller; Jing Tian; Linda P Fried
Journal:  J Am Coll Surg       Date:  2010-04-28       Impact factor: 6.113

9.  Accelerating the pace of surgical quality improvement: the power of hospital collaboration.

Authors:  Darrell A Campbell; Michael J Englesbe; James J Kubus; Laurel R S Phillips; Charles J Shanley; Vic Velanovich; Larry R Lloyd; Max C Hutton; Wallace A Arneson; David A Share
Journal:  Arch Surg       Date:  2010-10

10.  Identification of specific quality improvement opportunities for the elderly undergoing gastrointestinal surgery.

Authors:  David J Bentrem; Mark E Cohen; Denise M Hynes; Clifford Y Ko; Karl Y Bilimoria
Journal:  Arch Surg       Date:  2009-11
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  20 in total

1.  The importance of the first complication: understanding failure to rescue after emergent surgery in the elderly.

Authors:  Kyle H Sheetz; Robert W Krell; Michael J Englesbe; John D Birkmeyer; Darrell A Campbell; Amir A Ghaferi
Journal:  J Am Coll Surg       Date:  2014-05-09       Impact factor: 6.113

2.  Understanding Disparities in Surgical Outcomes for Medicaid Beneficiaries.

Authors:  Jake Claflin; Justin B Dimick; Darrell A Campbell; Michael J Englesbe; Kyle H Sheetz
Journal:  World J Surg       Date:  2019-04       Impact factor: 3.352

3.  The outcomes of the elderly in acute care general surgery.

Authors:  E St-Louis; M Sudarshan; M Al-Habboubi; M El-Husseini Hassan; D L Deckelbaum; T S Razek; L S Feldman; K Khwaja
Journal:  Eur J Trauma Emerg Surg       Date:  2015-04-08       Impact factor: 3.693

4.  Outcomes of Emergency Laparotomy (EL) Care Protocol at Tertiary Care Center from Low-Middle-Income Country (LMIC).

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Journal:  World J Surg       Date:  2018-05       Impact factor: 3.352

5.  Managing acute cholecystitis among Medicaid insured in New York State: opportunities to optimize care.

Authors:  Anne M Stey; Alexander J Greenstein; Arthur Aufses; Alan J Moskowitz; Natalia N Egorova
Journal:  Surg Endosc       Date:  2018-02-12       Impact factor: 4.584

Review 6.  Failure to rescue in surgical patients: A review for acute care surgeons.

Authors:  Justin S Hatchimonji; Elinore J Kaufman; Catherine E Sharoky; Lucy Ma; Anna E Garcia Whitlock; Daniel N Holena
Journal:  J Trauma Acute Care Surg       Date:  2019-09       Impact factor: 3.313

7.  Effects of the intermediate care unit on the oldest-old general surgical patients: a retrospective, pre- and postintervention study.

Authors:  Lichun Wang; Junpu Qing; Xiaofei Zhang; Lei Chen; Zheqing Li; Wen Xu; Lin Yao
Journal:  Aging Clin Exp Res       Date:  2020-07-31       Impact factor: 3.636

Review 8.  Importance of teamwork, communication and culture on failure-to-rescue in the elderly.

Authors:  A A Ghaferi; J B Dimick
Journal:  Br J Surg       Date:  2015-11-30       Impact factor: 6.939

9.  Clinical Effectiveness of the Elder-Friendly Approaches to the Surgical Environment Initiative in Emergency General Surgery.

Authors:  Rachel G Khadaroo; Lindsey M Warkentin; Adrian S Wagg; Raj S Padwal; Fiona Clement; Xiaoming Wang; William D Buie; Jayna Holroyd-Leduc
Journal:  JAMA Surg       Date:  2020-04-15       Impact factor: 14.766

10.  Impact of Hospital Characteristics on Failure to Rescue Following Major Surgery.

Authors:  Kyle H Sheetz; Justin B Dimick; Amir A Ghaferi
Journal:  Ann Surg       Date:  2016-04       Impact factor: 12.969

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