| Literature DB >> 23979112 |
Xiwei Zheng1, Michelle J Yoo, David S Hage.
Abstract
A multi-dimensional chromatographic approach was developed to measure the free fractions of drug enantiomers in samples that also contained a binding protein or serum. This method, which combined ultrafast affinity extraction with a chiral stationary phase, was demonstrated using the drug warfarin and the protein human serum albumin.Entities:
Mesh:
Substances:
Year: 2013 PMID: 23979112 PMCID: PMC3812820 DOI: 10.1039/c3an01315d
Source DB: PubMed Journal: Analyst ISSN: 0003-2654 Impact factor: 4.616