Literature DB >> 23979086

Autistic traits in children with and without ADHD.

Amelia Kotte1, Gagan Joshi, Ronna Fried, Mai Uchida, Andrea Spencer, K Yvonne Woodworth, Tara Kenworthy, Stephen V Faraone, Joseph Biederman.   

Abstract

OBJECTIVE: To assess the implications of autistic traits (ATs) in youth with attention-deficit/hyperactivity disorder (ADHD) without a diagnosis of autism.
METHODS: Participants were youth with (n = 242) and without (n = 227) ADHD and controls without ADHD in whom a diagnosis of autism was exclusionary. Assessment included measures of psychiatric, psychosocial, educational, and cognitive functioning. ATs were operationalized by using the withdrawn + social + thought problems T scores from the Child Behavior Checklist.
RESULTS: A positive AT profile was significantly overrepresented among ADHD children versus controls (18% vs 0.87%; P < .001). ADHD children with the AT profile were significantly more impaired than control subjects in psychopathology, interpersonal, school, family, and cognitive domains.
CONCLUSIONS: A substantial minority of ADHD children manifests ATs, and those exhibiting ATs have greater severity of illness and dysfunction.

Entities:  

Keywords:  ADD; ADHD; AT; attention deficit disorder; attention-deficit/hyperactivity disorder; autism traits; autistic traits; comorbidity; social disability

Mesh:

Year:  2013        PMID: 23979086      PMCID: PMC3876754          DOI: 10.1542/peds.2012-3947

Source DB:  PubMed          Journal:  Pediatrics        ISSN: 0031-4005            Impact factor:   7.124


  51 in total

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  28 in total

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Review 2.  Genetic targeting of the amphetamine and methylphenidate-sensitive dopamine transporter: on the path to an animal model of attention-deficit hyperactivity disorder.

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Review 7.  ADHD in children and youth: Part 3-Assessment and treatment with comorbid ASD, ID, or prematurity.

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Review 8.  Neuroimaging endophenotypes in autism spectrum disorder.

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10.  The Impact of the Comorbidity of ASD and ADHD on Social Impairment.

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