Literature DB >> 239735

The contribution of serum enzymes and carcinoembryonic antigen to the early diagnosis of metastatic colorectal cancer.

E H Cooper, R Turner, L Steele, A M Neville, A M Mackay.   

Abstract

The evolution of metastatic colorectal cancer in patients who have had surgical treatment for a primary lesion was studied in relation the progressive changes in the blood levels of carcinembryonic antigen (CEA), to gamma glutamyl transpeptidase (GGT) and routine liver function tests (LFTs). Involvement of the liver could ofter be reliably predicted many weeks in advance of clinical diagnosis while metastases to other sites were less likely to be detected early by this test. The association of the extent of disease with the patterns of biochemical changes is discussed with reference to several illustrative examples.

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Year:  1975        PMID： 239735      PMCID： PMC2009361          DOI： 10.1038/bjc.1975.13

Source DB:  PubMed          Journal:  Br J Cancer        ISSN： 0007-0920            Impact factor:   7.640


  7 in total

1.  Serial carcinoembryonic antigen assays. Use in detection of cancer recurrence.

Authors:  J J Sorokin; P H Sugarbaker; N Zamcheck; M Pisick; H Z Kupchik; F D Moore
Journal:  JAMA       Date:  1974-04-01       Impact factor: 56.272

2.  Role of serial plasma C.E.A. assays in detection of recurrent and metastatic colorectal carcinomas.

Authors:  A M Mackay; S Patel; S Carter; U Stevens; D J Laurence; E H Cooper; A M Neville
Journal:  Br Med J       Date:  1974-11-16

3.  Carcinoembryonic antigen: clinical correlation with chemotherapy for metastatic gastrointestinal cancer.

Authors:  A T Skarin; R Delwiche; N Zamcheck; J J Lokich; E Frei
Journal:  Cancer       Date:  1974-05       Impact factor: 6.860

4.  [Leucine aminopeptidase (arylamidase) activity in the serum. Determination using leucine-p-nitroanilide as substrate].

Authors:  F Willig; I Greiner; H Stork; F H Schmidt
Journal:  Klin Wochenschr       Date:  1967-05-01

5.  Gamma-glutamyl transpeptidase and 5'-nucleotidase. Comparison as diagnostics for hepatic disease.

Authors:  D J Boone; J I Routh; R Schrantz
Journal:  Am J Clin Pathol       Date:  1974-03       Impact factor: 2.493

6.  Blood muramidase activity in colorectal cancer.

Authors:  E H Cooper; R Turner; L Steele; J C Goligher
Journal:  Br Med J       Date:  1974-09-14

7.  Combination of carcinoembryonic antigen and gamma glutamyl transpeptidase in the study of the evolution of colorectal cancer.

Authors:  L Steele; E H Cooper; A M Mackay; M S Losowsky; J C Goligher
Journal:  Br J Cancer       Date:  1974-10       Impact factor: 7.640
  7 in total
  8 in total

1.  A suggested guiding panel of seromarkers for efficient discrimination between primary and secondary human hepatocarcinoma.

Authors:  Nabil Mohie Abdel-Hamid; M M Abouzied; M H Nazmy; M A Fawzy; A S Gerges
Journal:  Tumour Biol       Date:  2015-09-19

2.  Quantitation and immunochemical characterization of carcinoembryonic antigen and glucose phosphate isomerase in blood and washings of patients with gastric and colonic diseases.

Authors:  D Munjal; P G Brady
Journal:  Am J Dig Dis       Date:  1978-01

3.  Acute-phase reactant protein profiles: an aid to monitoring large bowel cancer by CEA and serum enzymes.

Authors:  A M Ward; E H Cooper; R Turner; J A Anderson; A M Neville
Journal:  Br J Cancer       Date:  1977-02       Impact factor: 7.640

4.  In vivo subcellular imaging of tumors in mouse models using a fluorophore-conjugated anti-carcinoembryonic antigen antibody in two-photon excitation microscopy.

Authors:  Shigehiro Koga; Yusuke Oshima; Naoki Honkura; Tadahiro Iimura; Kenji Kameda; Koichi Sato; Motohira Yoshida; Yuji Yamamoto; Yuji Watanabe; Atsuhiko Hikita; Takeshi Imamura
Journal:  Cancer Sci       Date:  2014-10       Impact factor: 6.716

5.  Novel anticarcinoembryonic antigen antibody-drug conjugate has antitumor activity in the existence of soluble antigen.

Authors:  Daisuke Shinmi; Ryosuke Nakano; Keisuke Mitamura; Minami Suzuki-Imaizumi; Junko Iwano; Yuya Isoda; Junichi Enokizono; Yasuhisa Shiraishi; Emi Arakawa; Kazuma Tomizuka; Kazuhiro Masuda
Journal:  Cancer Med       Date:  2017-02-17       Impact factor: 4.452

6.  Carcinoembryonic antigen and glucose phosphate isomerase in a human colonic cancer model (GW-39).

Authors:  D Munjal; D M Goldenberg
Journal:  Br J Cancer       Date:  1976-09       Impact factor: 7.640

7.  Measurement of high molecular weight forms of enzymes in serum in the detection of hepatic metastases of colorectal cancer.

Authors:  O J Traynor; C B Wood; Z O Echetebu; K B Whitaker; D W Moss
Journal:  Br J Cancer       Date:  1986-04       Impact factor: 7.640

8.  gamma-Glutamyltranspeptidase activity in human breast lesions: an unfavourable prognostic sign.

Authors:  S Bard; P Noël; F Chauvin; G Quash
Journal:  Br J Cancer       Date:  1986-05       Impact factor: 7.640
  8 in total

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