Literature DB >> 13805

Acute-phase reactant protein profiles: an aid to monitoring large bowel cancer by CEA and serum enzymes.

A M Ward, E H Cooper, R Turner, J A Anderson, A M Neville.   

Abstract

The profiles of 4 acute-phase reactant proteins (APRPs) (haptoglobin (HPT), alpha1 antitrypsin (AAT), alpha1 acid glycoprotein (AGP) and prealbumin (PALB)) have been studied during the evolution of bowel cancer. Serial measurements of these APRPs can add to the information obtained from measurements of the level of CEA and hepatic enzymes during the monitoring of postoperative patients. There is considerable stability in the profile in a given individual in health, Rises of AAT and AGP are associated with metastases. High levels of HPT may suggest involvement of the bowel wall by recurrent cancer. PALB levels tend to reflect the nutritional status. A discriminant function based on the log CEA, AAT and AGP preoperative blood levels can considerably improve on the predictive value attained using CEA levels alone.

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Year:  1977        PMID： 13805      PMCID： PMC2025326          DOI： 10.1038/bjc.1977.24

Source DB:  PubMed          Journal:  Br J Cancer        ISSN： 0007-0920            Impact factor:   7.640


  14 in total

1.  Disease activity and serum proteins in ulcerative colitis. Immunochemical quantitation.

Authors:  I L Marner; S Friborg; E Simonsen
Journal:  Scand J Gastroenterol       Date:  1975       Impact factor: 2.423

2.  ACCURACY OF ROENTGENOLOGIC EXAMINATION IN DETECTING CARCINOMA OF THE COLON.

Authors:  J D LAUER; H C CARLSON; E E WOLLAEGER
Journal:  Dis Colon Rectum       Date:  1965 May-Jun       Impact factor: 4.585

3.  Carcinoembryonic antigen and phosphohexose isomerase, gammaglutamyl transpeptidase and lactate dehydorgenase levels in patients with and without liver metastases.

Authors:  D Munjal; P L Chawla; J J Lokich; N Zamcheck
Journal:  Cancer       Date:  1976-04       Impact factor: 6.860

Review 4.  Laboratory aids to diagnosis--enzymes.

Authors:  M K Schwartz
Journal:  Cancer       Date:  1976-01       Impact factor: 6.860

5.  Genetic aspects of the Pi system.

Authors:  P J Cook
Journal:  Postgrad Med J       Date:  1974-06       Impact factor: 2.401

6.  Automated quantitation of proteins in serum and other biologic fluids.

Authors:  R F Ritchie; C A Alper; J Graves; N Pearson; C Larson
Journal:  Am J Clin Pathol       Date:  1973-02       Impact factor: 2.493

7.  Serum haptoglobins: a preoperative detector of metastatic renal carcinoma.

Authors:  M Vickers
Journal:  J Urol       Date:  1974-09       Impact factor: 7.450

8.  Serum haptoglobin in patients with ovarian malignancies.

Authors:  W K Mueller; R Handschumacher; M E Wade
Journal:  Obstet Gynecol       Date:  1971-09       Impact factor: 7.661

9.  Alpha-globulins in the surveillance of colorectal cancer.

Authors:  E H Cooper; R Turner; A Geekie; A M Neville; J C Goligher; N G Graham; G R Giles; R Hall; W A Macadam
Journal:  Biomedicine       Date:  1976-06

10.  The contribution of serum enzymes and carcinoembryonic antigen to the early diagnosis of metastatic colorectal cancer.

Authors:  E H Cooper; R Turner; L Steele; A M Neville; A M Mackay
Journal:  Br J Cancer       Date:  1975-01       Impact factor: 7.640
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  16 in total

1.  Drug-binding proteins in liver transplant patients.

Authors:  M L Huang; R Venkataramanan; G J Burckart; R J Ptachcinski; D H Van Thiel; T E Starzl
Journal:  J Clin Pharmacol       Date:  1988-06       Impact factor: 3.126

2.  Lack of effect of treatment with human recombinant-tumour necrosis factor (HrTNF) on the binding of quinidine to alpha 1-acid glycoprotein (AGP).

Authors:  J A Barnett; D E Brenner; P J Creaven; D Lalka
Journal:  Br J Clin Pharmacol       Date:  1989-02       Impact factor: 4.335

3.  Birmingham Medical Research Expeditionary Society 1977 Expedition: serum and urine proteins during a high altitude trek.

Authors:  A R Bradwell
Journal:  Postgrad Med J       Date:  1979-07       Impact factor: 2.401

4.  Biochemical profiles in tumour monitoring and their analysis.

Authors:  E H Cooper; T E Kenny
Journal:  Proc R Soc Med       Date:  1977-12

5.  Alpha1-antitrypsin deficiency carriers, serum alpha 1-antitrypsin concentration, and non-small cell lung cancer survival.

Authors:  Yan Li; Michael J Krowka; Yingwei Qi; Jerry A Katzmann; Yong Song; Yafei Li; Sumithra J Mandrekar; Ping Yang
Journal:  J Thorac Oncol       Date:  2011-02       Impact factor: 15.609

6.  Serum levels of alpha1-antitrypsin predict phenotypic expression of the alpha1-antitrypsin gene.

Authors:  Steven J Steiner; Sandeep K Gupta; Joseph M Croffie; Joseph F Fitzgerald
Journal:  Dig Dis Sci       Date:  2003-09       Impact factor: 3.199

7.  Immunosuppressive effect of acute-phase reactant proteins in vitro and its relevance to cancer.

Authors:  R Samak; R Edelstein; L Israel
Journal:  Cancer Immunol Immunother       Date:  1982       Impact factor: 6.968

8.  Immunological studies of patients with tumours of the prostate and bladder (a retrospective analysis).

Authors:  I Romics; J Fehér; J Horváth
Journal:  Int Urol Nephrol       Date:  1983       Impact factor: 2.370

9.  Immunosuppressive acidic protein serum levels in breast cancer patients in a reference to CA 15-3 levels.

Authors:  A D Cohen; Y Shoenfeld; J Gopas; Y Cohen
Journal:  Breast Cancer Res Treat       Date:  1994       Impact factor: 4.872

10.  Blueberry husks and probiotics attenuate colorectal inflammation and oncogenesis, and liver injuries in rats exposed to cycling DSS-treatment.

Authors:  Asa Håkansson; Camilla Bränning; Göran Molin; Diya Adawi; Marie-Louise Hagslätt; Bengt Jeppsson; Margareta Nyman; Siv Ahrné
Journal:  PLoS One       Date:  2012-03-23       Impact factor: 3.240
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