BACKGROUND: Helicobacter pylori is the most common chronic bacterial infection, and a significant aetiological factor in acid peptic diseases and gastric cancer. Dyspepsia is a common gastrointestinal disorder, and the most common indication for gastroscopy. Detection of this organism during endoscopy has become standard clinical practice. We determine the prevalence of H. pylori infection among dyspeptic patients using serology and histology. METHODS: Patients with dyspepsia underwent gastroscopy, and biopsies were taken from the antral portions of their stomach and processed. Their serum samples were tested for H. pylori infection using ELISA to detect anti-bodies. RESULTS: One hundred and twenty-five patients, comprising 49 (39.2%) males and 76 (60.8%) females were studied. A prevalence rate of 93.6% for H. pylori was found by serology while a rate of 80.0% was found by histology. CONCLUSION: There is a high prevalence of H. pylori infection in patients with dyspepsia; and a high percentage of detection by serological and histological tests.
BACKGROUND:Helicobacter pylori is the most common chronic bacterial infection, and a significant aetiological factor in acid peptic diseases and gastric cancer. Dyspepsia is a common gastrointestinal disorder, and the most common indication for gastroscopy. Detection of this organism during endoscopy has become standard clinical practice. We determine the prevalence of H. pyloriinfection among dyspeptic patients using serology and histology. METHODS:Patients with dyspepsia underwent gastroscopy, and biopsies were taken from the antral portions of their stomach and processed. Their serum samples were tested for H. pyloriinfection using ELISA to detect anti-bodies. RESULTS: One hundred and twenty-five patients, comprising 49 (39.2%) males and 76 (60.8%) females were studied. A prevalence rate of 93.6% for H. pylori was found by serology while a rate of 80.0% was found by histology. CONCLUSION: There is a high prevalence of H. pyloriinfection in patients with dyspepsia; and a high percentage of detection by serological and histological tests.
Authors: Siraji Obayo; Conrad Muzoora; Ponsiano Ocama; Matthew M Cooney; Tony Wilson; Christopher S Probert Journal: Afr Health Sci Date: 2015-09 Impact factor: 0.927
Authors: Elena Pomari; Tamara Ursini; Ronaldo Silva; Martina Leonardi; Marco Ligozzi; Andrea Angheben Journal: J Clin Med Date: 2020-07-24 Impact factor: 4.241