Literature DB >> 23960849

A case report from Nepalese community pharmacy on levofloxacin induced severe abdominal pain.

K C Bhuvan1, Alian A Alrasheedy, Mohamed Izham Mohamed Ibrahim.   

Abstract

A 46-year-old female patient developed severe abdominal pain shortly after taking levofloxacin, 1000 mg for acute bacterial sinusitis. The pain started after taking the first dose of levofloxacin and became worse after the second dose. The patient was unable to do daily physical activities. The pain resolved upon discontinuation of levofloxacin and symptomatic therapy. Other factors that may cause abdominal pain were ruled out. This case is of interest as it documents severe abdominal pain due to levofloxacin requiring discontinuation of therapy and describes its appropriate management. In addition, it highlights the vital role that community pharmacists could play in managing adverse drug reactions (ADRs) and preventing potential Drug Related Problems (DRPs).

Entities:  

Keywords:  Abdominal pain; Community pharmacist; Levofloxacin; Nepal

Year:  2013        PMID: 23960849      PMCID: PMC3745175          DOI: 10.1016/j.jsps.2013.04.006

Source DB:  PubMed          Journal:  Saudi Pharm J        ISSN: 1319-0164            Impact factor:   4.330


  5 in total

1.  A trial of high-dose, short-course levofloxacin for the treatment of acute bacterial sinusitis.

Authors:  Michael Poole; Jack Anon; Margaret Paglia; Jim Xiang; Mohammed Khashab; James Kahn
Journal:  Otolaryngol Head Neck Surg       Date:  2006-01       Impact factor: 3.497

2.  Levofloxacin-induced tendinopathy of the hip.

Authors:  Corrine M Ganske; Kristin K Horning
Journal:  Ann Pharmacother       Date:  2012-04-24       Impact factor: 3.154

3.  A method for estimating the probability of adverse drug reactions.

Authors:  C A Naranjo; U Busto; E M Sellers; P Sandor; I Ruiz; E A Roberts; E Janecek; C Domecq; D J Greenblatt
Journal:  Clin Pharmacol Ther       Date:  1981-08       Impact factor: 6.875

4.  Clinical practice guideline: adult sinusitis.

Authors:  Richard M Rosenfeld; David Andes; Neil Bhattacharyya; Dickson Cheung; Steven Eisenberg; Theodore G Ganiats; Andrea Gelzer; Daniel Hamilos; Richard C Haydon; Patricia A Hudgins; Stacie Jones; Helene J Krouse; Lawrence H Lee; Martin C Mahoney; Bradley F Marple; Col John P Mitchell; Robert Nathan; Richard N Shiffman; Timothy L Smith; David L Witsell
Journal:  Otolaryngol Head Neck Surg       Date:  2007-09       Impact factor: 3.497

5.  Safety of fluoroquinolones: An update.

Authors:  L Mandell; G Tillotson
Journal:  Can J Infect Dis       Date:  2002-01
  5 in total
  1 in total

1.  Bibliometric analysis of adverse drug reactions and pharmacovigilance research activities in Nepal.

Authors:  Sunil Shrestha; Krisha Danekhu; Bhuvan Kc; Subish Palaian; Mohamed Izham Mohamed Ibrahim
Journal:  Ther Adv Drug Saf       Date:  2020-06-12
  1 in total

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