Literature DB >> 23960814

Quinoline: A versatile heterocyclic.

Akranth Marella1, Om Prakash Tanwar, Rikta Saha, Mohammad Rahmat Ali, Sandeep Srivastava, Mymoona Akhter, Mohammad Shaquiquzzaman, Mohammad Mumtaz Alam.   

Abstract

Quinoline or 1-aza-naphthalene is a weak tertiary base. Quinoline ring has been found to possess antimalarial, anti-bacterial, antifungal, anthelmintic, cardiotonic, anticonvulsant, anti-inflammatory, and analgesic activity. Quinoline not only has a wide range of biological and pharmacological activities but there are several established protocols for the synthesis of this ring. The article aims at highlighting these very diversities of the ring.

Entities:  

Keywords:  Biological activity; Quinoline; Synthesis

Year:  2012        PMID： 23960814      PMCID： PMC3744984          DOI： 10.1016/j.jsps.2012.03.002

Source DB:  PubMed          Journal:  Saudi Pharm J        ISSN： 1319-0164            Impact factor:   4.330


  55 in total

1.  New quinoline derivatives: synthesis and investigation of antibacterial and antituberculosis properties.

Authors:  Sumesh Eswaran; Airody Vasudeva Adhikari; Imran H Chowdhury; Nishith K Pal; K D Thomas
Journal:  Eur J Med Chem       Date:  2010-04-28       Impact factor: 6.514

2.  Design, synthesis, and biological evaluation of novel quinoline derivatives as HIV-1 Tat-TAR interaction inhibitors.

Authors:  Shuguang Chen; Ran Chen; Meizi He; Ruifang Pang; Zhiwu Tan; Ming Yang
Journal:  Bioorg Med Chem       Date:  2009-01-23       Impact factor: 3.641

3.  Structure-activity relationships for a series of quinoline-based compounds active against replicating and nonreplicating Mycobacterium tuberculosis.

Authors:  Annamaria Lilienkampf; Jialin Mao; Baojie Wan; Yuehong Wang; Scott G Franzblau; Alan P Kozikowski
Journal:  J Med Chem       Date:  2009-04-09       Impact factor: 7.446

4.  Identification of 4-hydroxyquinolines inhibitors of p300/CBP histone acetyltransferases.

Authors:  Antonello Mai; Dante Rotili; Domenico Tarantino; Angela Nebbioso; Sabrina Castellano; Gianluca Sbardella; Marc Tini; Lucia Altucci
Journal:  Bioorg Med Chem Lett       Date:  2008-12-30       Impact factor: 2.823

5.  Novel tacrine-8-hydroxyquinoline hybrids as multifunctional agents for the treatment of Alzheimer's disease, with neuroprotective, cholinergic, antioxidant, and copper-complexing properties.

Authors:  María Isabel Fernández-Bachiller; Concepción Pérez; Gema C González-Muñoz; Santiago Conde; Manuela G López; Mercedes Villarroya; Antonio G García; María Isabel Rodríguez-Franco
Journal:  J Med Chem       Date:  2010-07-08       Impact factor: 7.446

6.  Antimalarial activity of novel 5-aryl-8-aminoquinoline derivatives.

Authors:  Hiroaki Shiraki; Michael P Kozar; Victor Melendez; Thomas H Hudson; Colin Ohrt; Alan J Magill; Ai J Lin
Journal:  J Med Chem       Date:  2010-12-08       Impact factor: 7.446

7.  2-substituted quinoline alkaloids as potential antileishmanial drugs.

Authors:  A Fournet; A A Barrios; V Muñoz; R Hocquemiller; A Cavé; J Bruneton
Journal:  Antimicrob Agents Chemother       Date:  1993-04       Impact factor: 5.191

8.  Studies on anti-HIV quinolones: new insights on the C-6 position.

Authors:  Serena Massari; Dirk Daelemans; Giuseppe Manfroni; Stefano Sabatini; Oriana Tabarrini; Christophe Pannecouque; Violetta Cecchetti
Journal:  Bioorg Med Chem       Date:  2008-12-03       Impact factor: 3.641

9.  5-Lipoxygenase-activating protein is the target of a quinoline class of leukotriene synthesis inhibitors.

Authors:  J F Evans; C Lévillé; J A Mancini; P Prasit; M Thérien; R Zamboni; J Y Gauthier; R Fortin; P Charleson; D E MacIntyre
Journal:  Mol Pharmacol       Date:  1991-07       Impact factor: 4.436

10.  Tetrahydro-4-quinolinamines identified as novel P2Y(1) receptor antagonists.

Authors:  Angel I Morales-Ramos; John S Mecom; Terry J Kiesow; Todd L Graybill; Gregory D Brown; Nambi V Aiyar; Elizabeth A Davenport; Lorena A Kallal; Beth A Knapp-Reed; Peng Li; Allyn T Londregan; Dwight M Morrow; Shobha Senadhi; Reema K Thalji; Steve Zhao; Cynthia L Burns-Kurtis; Joseph P Marino
Journal:  Bioorg Med Chem Lett       Date:  2008-10-02       Impact factor: 2.823
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  28 in total

1.  Facilely accessible quinoline derivatives as potent antibacterial agents.

Authors:  Peng Teng; Chunhui Li; Zhong Peng; Vanderschouw Anne Marie; Alekhya Nimmagadda; Ma Su; Yaqiong Li; Xingmin Sun; Jianfeng Cai
Journal:  Bioorg Med Chem       Date:  2018-05-22       Impact factor: 3.641

2.  Synergistic Effect of Biogenics Derived from Potential Probiotics Together with Zingerone Against Biofilm Formation by Pseudomonas aeruginosa PAO1.

Authors:  Swati Chandla; Kusum Harjai; Geeta Shukla
Journal:  Probiotics Antimicrob Proteins       Date:  2021-03-30       Impact factor: 4.609

3.  The regioselective one-pot four-component synthesis of novel functionalized 4H-pyrano[2, 3-b]quinoline derivatives using DABCO as a homogeneous organocatalyst.

Authors:  Masumeh Heydari; Ali Asghar Mohammadi; Mohammadreza Mosleh
Journal:  Mol Divers       Date:  2022-09-07       Impact factor: 3.364

4.  Synthesis, SAR studies, and insecticidal activities of certain N-heterocycles derived from 3-((2-chloroquinolin-3-yl)methylene)-5-phenylfuran-2(3H)-one against Culex pipiens L. larvae.

Authors:  Sayed K Ramadan; Doaa R Abdel Haleem; Hisham S M Abd-Rabboh; Nourhan M Gad; Wael S I Abou-Elmagd; David S A Haneen
Journal:  RSC Adv       Date:  2022-05-05       Impact factor: 4.036

5.  Synthesis and evaluation of the in vitro and in vivo antitrypanosomal activity of 2-styrylquinolines.

Authors:  Roger Espinosa; Sara Robledo; Camilo Guzmán; Natalia Arbeláez; Lina Yepes; Gílmar Santafé; Alex Sáez
Journal:  Heliyon       Date:  2021-05-12

Review 6.  Solvent-free incorporation of CO2 into 2-oxazolidinones: a review.

Authors:  Sattar Arshadi; Alireza Banaei; Saeideh Ebrahimiasl; Aazam Monfared; Esmail Vessally
Journal:  RSC Adv       Date:  2019-06-21       Impact factor: 4.036

7.  Crystal structures of five (2-chloro-quinolin-3-yl)methyl ethers: supra-molecular assembly in one and two dimensions mediated by hydrogen bonding and π-π stacking.

Authors:  Haliwana B V Sowmya; Tholappanavara H Suresha Kumara; Nagendrappa Gopalpur; Jerry P Jasinski; Sean P Millikan; Hemmige S Yathirajan; Christopher Glidewell
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2015-05-13

8.  The crystal structure of 3-chloro-2-(4-methyl-phenyl)-2H-pyrazolo-[3,4-b]quinoline.

Authors:  Haliwana B V Sowmya; Tholappanavara H Suresha Kumara; Jerry P Jasinski; Sean P Millikan; Hemmige S Yathirajan; Christopher Glidewell
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2015-04-30

9.  Structure-based drug discovery for combating influenza virus by targeting the PA-PB1 interaction.

Authors:  Ken Watanabe; Takeshi Ishikawa; Hiroki Otaki; Satoshi Mizuta; Tsuyoshi Hamada; Takehiro Nakagaki; Daisuke Ishibashi; Shuzo Urata; Jiro Yasuda; Yoshimasa Tanaka; Noriyuki Nishida
Journal:  Sci Rep       Date:  2017-08-25       Impact factor: 4.379

10.  Design and green synthesis of novel quinolinone derivatives of potential anti-breast cancer activity against MCF-7 cell line targeting multi-receptor tyrosine kinases.

Authors:  Mohamed Mokhtar; Khadijah S Alghamdi; Nesreen S Ahmed; Dina Bakhotmah; Tamer S Saleh
Journal:  J Enzyme Inhib Med Chem       Date:  2021-12       Impact factor: 5.051
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