Literature DB >> 23960768

Toxic effect of Cadmium found in eyeliner to the eye of a 21 year old Saudi woman: A case report.

Mohamed Al Amry1, Fahad Al-Saikhan, Ayman Ayoubi.   

Abstract

PURPOSE: To raise the issue of increased use of traditional medicine while the Tertiary care hospitals are available to provide the appropriate care for each clinical condition. Eyeliner (Kohl) is an Arabic word denoting a fine powder with a texture and appearance similar to mascara. It is usually worn on the lid margins or inside the conjunctival sac by Middle and Far Eastern and in East Africans populations for different purposes like beauty or religious and as a treatment for many eye diseases.
SUMMARY: We report a case of a lady who put traditional locally prepared eyeliner in her eye that resulted in severe corneal edema and faint scaring. On toxicology analysis it was discovered to contain toxic levels of Cadmium (Cd) and Lead (Pb).
CONCLUSION: Cd is a heavy toxic metal like Pb but has never been reported as a component of eyeliners. The most likely possible cause of the corneal clinical picture in our case is due to the toxic effect of Cd found in the traditional eyeliner (Kohl) used in Saudi Arabia.

Entities:  

Keywords:  Cadmium; Eye; Eyeliner; Kohl; Toxic effect

Year:  2011        PMID: 23960768      PMCID: PMC3745197          DOI: 10.1016/j.jsps.2011.05.002

Source DB:  PubMed          Journal:  Saudi Pharm J        ISSN: 1319-0164            Impact factor:   4.330


  6 in total

1.  Inhibition of corneal epithelial cell migration by cadmium and mercury.

Authors:  J L Ubels; T B Osgood
Journal:  Bull Environ Contam Toxicol       Date:  1991-02       Impact factor: 2.151

2.  Low levels of cadmium chloride damage the corneal endothelium.

Authors:  W J Weidner; A J Sillman
Journal:  Arch Toxicol       Date:  1997       Impact factor: 5.153

Review 3.  Kohl (surma): retrospect and prospect.

Authors:  Zafar Alam Mahmood; S M S Zoha; Khan Usmanghani; Muhammad Mohtasheemul Hasan; Obaid Ali; Sarwat Jahan; Aftab Saeed; Rabail Zaihd; Misbah Zubair
Journal:  Pak J Pharm Sci       Date:  2009-01       Impact factor: 0.684

4.  Heavy metal concentrations in human eyes.

Authors:  Jay C Erie; John A Butz; Jonathan A Good; Elizabeth A Erie; Mary F Burritt; J Douglas Cameron
Journal:  Am J Ophthalmol       Date:  2005-05       Impact factor: 5.258

5.  Kohl: a hazardous eyeliner.

Authors:  S A al-Hazzaa; P M Krahn
Journal:  Int Ophthalmol       Date:  1995       Impact factor: 2.031

6.  Cadmium toxicity to the cornea of pregnant rats: electron microscopy and x-ray microanalysis.

Authors:  M Yoshizuka; K J McCarthy; G I Kaye; S Fujimoto
Journal:  Anat Rec       Date:  1990-05
  6 in total
  7 in total

1.  Morphological, biochemical, and histopathological postmortem ocular indices following subchronic exposure to cadmium and/or lead in a rabbit model.

Authors:  Yasmina Mohammed Abd-Elhakim; Nabela I El Sharkawy; Khlood M El Bohy; Mohammed Gomaa; Sarah Haseeb
Journal:  Environ Sci Pollut Res Int       Date:  2017-12-19       Impact factor: 4.223

2.  The impacts of individual and combined exposure to cadmium and lead on intraocular pressure, electroretinography, and residual changes in the rabbit eyes.

Authors:  Yasmina M Abd-Elhakim; Khlood M El Bohi; Nabela I El Sharkawy; Manar A Ghali; Sarah Haseeb
Journal:  Environ Sci Pollut Res Int       Date:  2019-09-13       Impact factor: 4.223

3.  Corneal Epitheliopathy After Trauma by Fake Snow Powder in a 7-year-old Child.

Authors:  Mohammad A Al-Amry; Huda A Al-Ghadeer
Journal:  Middle East Afr J Ophthalmol       Date:  2016 Jul-Sep

4.  Evaluation of heavy metals in cosmetic products and their health risk assessment.

Authors:  Hamna Arshad; Moniba Zahid Mehmood; Munir Hussain Shah; Arshad Mehmood Abbasi
Journal:  Saudi Pharm J       Date:  2020-05-29       Impact factor: 4.330

Review 5.  A Review of Corneal Endotheliitis and Endotheliopathy: Differential Diagnosis, Evaluation, and Treatment.

Authors:  Majid Moshirfar; Michael S Murri; Tirth J Shah; David F Skanchy; James Q Tuckfield; Yasmyne C Ronquillo; Orry C Birdsong; Daniel Hofstedt; Phillip C Hoopes
Journal:  Ophthalmol Ther       Date:  2019-03-11

6.  Toxic Elements in Traditional Kohl-Based Eye Cosmetics in Spanish and German Markets.

Authors:  Elisabet Navarro-Tapia; Mariona Serra-Delgado; Lucía Fernández-López; Montserrat Meseguer-Gilabert; María Falcón; Giorgia Sebastiani; Sebastian Sailer; Oscar Garcia-Algar; Vicente Andreu-Fernández
Journal:  Int J Environ Res Public Health       Date:  2021-06-05       Impact factor: 3.390

7.  A common response to common danger? Comparison of animal and plant signaling pathways involved in cadmium sensing.

Authors:  Jagna Chmielowska-Bąk; Joanna Deckert
Journal:  J Cell Commun Signal       Date:  2012-08-04       Impact factor: 5.782

  7 in total

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