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Literature DB >> 23959851

Nanotechnology-based drug delivery systems for targeting, imaging and diagnosis of neurodegenerative diseases.

Abstract

Neurodegenerative disorders are becoming prevalent with the increasing age of the general population. A number of difficulties have emerged for the potential treatment of neurodegenerative diseases, as these disorders may be multi systemic in nature. Due to limitations regarding the blood brain barrier (BBB) structure, efflux pumps and metabolic enzyme expression, conventional drug delivery systems do not provide efficient therapy for neurodegenerative disorders. Nanotechnology can offer impressive improvement of the neurodegenerative disease treatment by using bio-engineered systems interacting with biological systems at a molecular level. This review focuses on the nano-enabled system applications for the treatment and diagnosis of neurodegenerative diseases, in particular Alzheimer’s, Parkinson’s and Prion diseases.

Entities: Disease Species

Mesh：

Substances：
Drug Carriers

Year: 2013 PMID： 23959851 DOI： 10.1007/s11095-013-1156-7

Source DB: PubMed Journal: Pharm Res ISSN： 0724-8741 Impact factor: 4.200

110 in total

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Review 2. Improving the transport of chemotherapeutic drugs across the blood-brain barrier.

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Authors: Hari Shanker Sharma; Aruna Sharma
Journal: CNS Neurol Disord Drug Targets Date: 2012-02 Impact factor: 4.388

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Review 5. Biopharmaceutical drug targeting to the brain.

Authors: William M Pardridge
Journal: J Drug Target Date: 2010-04 Impact factor: 5.121

6. Transport of a caspase inhibitor across the blood-brain barrier by chitosan nanoparticles.

Authors: Müge Yemişci; Yasemin Gürsoy-Özdemir; Seçil Caban; Ebru Bodur; Yılmaz Capan; Turgay Dalkara
Journal: Methods Enzymol Date: 2012 Impact factor: 1.600

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Journal: Ann N Y Acad Sci Date: 2010-01 Impact factor: 5.691

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Journal: Biochim Biophys Acta Date: 2005-09-25

Review 9. Neurogenic bowel dysfunction in patients with spinal cord injury, myelomeningocele, multiple sclerosis and Parkinson's disease.

Authors: Richard A Awad
Journal: World J Gastroenterol Date: 2011-12-14 Impact factor: 5.742

10. Nanosized zinc oxide particles induce neural stem cell apoptosis.

Authors: Xiaoyong Deng; Qixia Luan; Wenting Chen; Yanli Wang; Minghong Wu; Haijiao Zhang; Zheng Jiao
Journal: Nanotechnology Date: 2009-02-24 Impact factor: 3.874

16 in total

Review 1. 3D in vitro modeling of the central nervous system.

Authors: Amy M Hopkins; Elise DeSimone; Karolina Chwalek; David L Kaplan
Journal: Prog Neurobiol Date: 2014-11-22 Impact factor: 11.685

Review 2. GABA-containing liposomes: neuroscience applications and translational perspectives for targeting neurological diseases.

Authors: Marco Antônio Peliky Fontes; Gisele Cristiane Vaz; Thais Zielke Dias Cardoso; Mariana Flávia de Oliveira; Maria José Campagnole-Santos; Robson Augusto Souza Dos Santos; Neeru M Sharma; Kaushik P Patel; Frédéric Frézard
Journal: Nanomedicine Date: 2017-12-24 Impact factor: 5.307

3. An in vitro Blood-brain Barrier Model to Study the Penetration of Nanoparticles.

Authors: Sezin Aday; Wen Li; Jeffrey M Karp; Nitin Joshi
Journal: Bio Protoc Date: 2022-02-20

4. Delivery strategies for cell-based therapies in the brain: overcoming multiple barriers.

Authors: Olivia M Turk; Ryan C Woodall; Margarita Gutova; Christine E Brown; Russell C Rockne; Jennifer M Munson
Journal: Drug Deliv Transl Res Date: 2021-10-30 Impact factor: 5.671

5. RGD-modified liposomes enhance efficiency of aclacinomycin A delivery: evaluation of their effect in lung cancer.

Authors: Chan Feng; Xiaoyan Li; Chunyan Dong; Xuemei Zhang; Xie Zhang; Yong Gao
Journal: Drug Des Devel Ther Date: 2015-08-11 Impact factor: 4.162

Review 6. The janus facet of nanomaterials.

Authors: Julianna Kardos; Katalin Jemnitz; István Jablonkai; Attila Bóta; Zoltán Varga; Júlia Visy; László Héja
Journal: Biomed Res Int Date: 2015-05-17 Impact factor: 3.411