Literature DB >> 23957097

Clinical features of oral cancer.

Aw van Zyl1, B K Bunn.   

Abstract

Oral cancer (OC) is a major cause of global morbidity and mortality Squamous cell carcinoma accounts for more than 90% of oral malignancies and occurs most frequently in middle-aged to elderly patients who smoke and drink heavily. The overall outlook for patients diagnosed with oral squamous cell carcinoma (OSCC) remains poor, largely due to late clinical presentation. Early lesions are frequently undetected due to the lack of accompanying symptoms. Early recognition, diagnosis and treatment of OSCC significantly enhance patient survival and minimise the need for extensive surgery. It is thus essential that the oral health care worker (OHW) be familiar with the variable clinical manifestations of both potentially malignant disorders (PMD) as well as invasive malignancy. OC screening, particularly in high-risk patients should be an integral component of routine intra-oral clinical examination. The aim of this article is to highlight the varied clinical appearance of OC and to emphasise the importance of early recognition and diagnosis.

Entities:  

Mesh:

Year:  2012        PMID: 23957097

Source DB:  PubMed          Journal:  SADJ        ISSN: 1029-4864


  8 in total

1.  Roles of miR-138 and ISG15 in oral squamous cell carcinoma.

Authors:  Qimei Zhang; Yi He; Minhai Nie; Wei Cai
Journal:  Exp Ther Med       Date:  2017-07-09       Impact factor: 2.447

2.  TRG-AS1 is a potent driver of oncogenicity of tongue squamous cell carcinoma through microRNA-543/Yes-associated protein 1 axis regulation.

Authors:  Shuwei He; Xu Wang; Jingjing Zhang; Fan Zhou; Lei Li; Xingmin Han
Journal:  Cell Cycle       Date:  2020-07-02       Impact factor: 4.534

Review 3.  Peripheral Exophytic Oral Lesions: A Clinical Decision Tree.

Authors:  Hamed Mortazavi; Yaser Safi; Maryam Baharvand; Somayeh Rahmani; Soudeh Jafari
Journal:  Int J Dent       Date:  2017-07-05

4.  Differential Expression of Prostaglandin I2 Synthase Associated with Arachidonic Acid Pathway in the Oral Squamous Cell Carcinoma.

Authors:  Anelise Russo; Patrícia M Biselli-Chicote; Rosa S Kawasaki-Oyama; Márcia M U Castanhole-Nunes; José V Maniglia; Dalísio de Santi Neto; Érika C Pavarino; Eny M Goloni-Bertollo
Journal:  J Oncol       Date:  2018-11-08       Impact factor: 4.375

5.  Icariin Mitigates the Growth and Invasion Ability of Human Oral Squamous Cell Carcinoma via Inhibiting Toll-Like Receptor 4 and Phosphorylation of NF-κB P65.

Authors:  Ke Lei; Bing Ma; Ping Shi; Che Jin; Tan Ling; Longjiang Li; Xiangyi He; Lunchang Wang
Journal:  Onco Targets Ther       Date:  2020-01-10       Impact factor: 4.147

6.  Bupivacaine inhibits the malignant biological behavior of oral squamous cell carcinoma cells by inhibiting the activation of ERK1/2 and STAT3.

Authors:  Zhongchao Wang; Jie Zhang; Yongmei Wen; Pin Wang; Liyuan Fan
Journal:  Ann Transl Med       Date:  2021-05

7.  Effects of insulin-like growth factor binding protein 3 on cell growth and tumorigenesis in oral squamous cell carcinoma.

Authors:  Hong-Yuan Xu; Dong-Wang Zhu; Lai-Ping Zhong; Zhi-Yuan Zhang; Cheng-Zhe Yang; Xiao Yang; Peng Zhang
Journal:  Transl Cancer Res       Date:  2019-09       Impact factor: 1.241

8.  Evaluation of head and neck cancer education at European dental schools.

Authors:  Marcella R Poelman; Henk S Brand; Laura Foppen; Jan G A M de Visscher; Derk H Jan Jager
Journal:  Eur J Dent Educ       Date:  2021-05-24       Impact factor: 2.528

  8 in total

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