Literature DB >> 2395161

No evidence for genetic linkage of Gilles de la Tourette syndrome on chromosomes 7 and 18.

P Heutink1, B J van de Wetering, G J Breedveld, J Weber, L A Sandkuyl, E J Devor, A Heiberg, M F Niermeijer, B A Oostra.   

Abstract

Gilles de la Tourette syndrome is a heritable neuropsychiatric disorder. In order to determine the chromosomal localisation of the locus involved, genetic linkage studies were initiated in six extended families. The Gilles de la Tourette gene has been tentatively assigned to chromosome 18q22.1. In our present study no evidence for genetic linkage on chromosome 18 and chromosome 7 was obtained. Data from the markers tested made it possible to exclude the whole of chromosome 18 and the chromosome 7q21.3-qter region as a site for the Gilles de la Tourette gene.

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Year:  1990        PMID： 2395161      PMCID： PMC1017180          DOI： 10.1136/jmg.27.7.433

Source DB:  PubMed          Journal:  J Med Genet        ISSN： 0022-2593            Impact factor:   6.318


  18 in total

1.  Identification and regional localization of DNA markers on chromosome 7 for the cloning of the cystic fibrosis gene.

Authors:  J M Rommens; S Zengerling; J Burns; G Melmer; B S Kerem; N Plavsic; M Zsiga; D Kennedy; D Markiewicz; R Rozmahel
Journal:  Am J Hum Genet       Date:  1988-11       Impact factor: 11.025

2.  The nucleotide sequence of chicken smooth muscle myosin light chain two.

Authors:  P J Zavodny; M E Petro; C C Kumar; S H Dailey; H K Lonial; S K Narula; P J Leibowitz
Journal:  Nucleic Acids Res       Date:  1988-02-11       Impact factor: 16.971

Review 3.  Report of the committee on the genetic constitution of chromosomes 7 and 8.

Authors:  L C Tsui; M Farrall; H Donis-Keller
Journal:  Cytogenet Cell Genet       Date:  1989

4.  Report of the committee for chromosomes 17, 18, and 19.

Authors:  D Shaw; H Eiberg
Journal:  Cytogenet Cell Genet       Date:  1987

5.  Twelve loci form a continuous linkage map for human chromosome 18.

Authors:  P O'Connell; G M Lathrop; M Leppert; Y Nakamura; U Müller; J M Lalouel; R White
Journal:  Genomics       Date:  1988-11       Impact factor: 5.736

6.  A candidate for the cystic fibrosis locus isolated by selection for methylation-free islands.

Authors:  X Estivill; M Farrall; P J Scambler; G M Bell; K M Hawley; N J Lench; G P Bates; H C Kruyer; P A Frederick; P Stanier
Journal:  Nature       Date:  1987 Apr 30-May 6       Impact factor: 49.962

7.  A frequent Pvu II RFLP of the human gastrin releasing peptide gene.

Authors:  S D Detera-Wadleigh; S Anderson; E R Spindel
Journal:  Nucleic Acids Res       Date:  1987-01-12       Impact factor: 16.971

8.  Gene location in Tourette syndrome.

Authors:  D Donnai
Journal:  Lancet       Date:  1987-03-14       Impact factor: 79.321

9.  Genetic linkage is excluded for the D2-dopamine receptor lambda HD2G1 and flanking loci on chromosome 11q22-q23 in Tourette syndrome.

Authors:  E J Devor; D K Grandy; O Civelli; M Litt; A K Burgess; K E Isenberg; B J van de Wetering; B Oostra
Journal:  Hum Hered       Date:  1990       Impact factor: 0.444

10.  The inheritance of Gilles de la Tourette's syndrome and associated behaviors. Evidence for autosomal dominant transmission.

Authors:  D L Pauls; J F Leckman
Journal:  N Engl J Med       Date:  1986-10-16       Impact factor: 91.245
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  7 in total

Review 1.  The genetics of Tourette syndrome.

Authors:  D L Pauls
Journal:  Curr Psychiatry Rep       Date:  2001-04       Impact factor: 5.285

2.  Tourette syndrome in a pedigree with a 7;18 translocation: identification of a YAC spanning the translocation breakpoint at 18q22.3.

Authors:  L Boghosian-Sell; D E Comings; J Overhauser
Journal:  Am J Hum Genet       Date:  1996-11       Impact factor: 11.025

Review 3.  Quest for the elusive genetic basis of Tourette syndrome.

Authors:  P I Patel
Journal:  Am J Hum Genet       Date:  1996-11       Impact factor: 11.025

4.  A complete genome screen in sib pairs affected by Gilles de la Tourette syndrome. The Tourette Syndrome Association International Consortium for Genetics.

Authors: 
Journal:  Am J Hum Genet       Date:  1999-11       Impact factor: 11.025

5.  Linkage studies on Gilles de la Tourette syndrome: what is the strategy of choice?

Authors:  P Heutink; B J van de Wetering; A J Pakstis; R Kurlan; P Sandor; B A Oostra; L A Sandkuijl
Journal:  Am J Hum Genet       Date:  1995-08       Impact factor: 11.025

6.  Progress in the search for genetic linkage with Tourette syndrome: an exclusion map covering more than 50% of the autosomal genome.

Authors:  A J Pakstis; P Heutink; D L Pauls; R Kurlan; B J van de Wetering; J F Leckman; L A Sandkuyl; J R Kidd; G J Breedveld; C M Castiglione
Journal:  Am J Hum Genet       Date:  1991-02       Impact factor: 11.025

7.  Doctor Samuel Johnson: 'the great convulsionary' a victim of Gilles de la Tourette's syndrome.

Authors:  J M Pearce
Journal:  J R Soc Med       Date:  1994-07       Impact factor: 18.000
  7 in total

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