Literature DB >> 2335364

Genetic linkage is excluded for the D2-dopamine receptor lambda HD2G1 and flanking loci on chromosome 11q22-q23 in Tourette syndrome.

E J Devor1, D K Grandy, O Civelli, M Litt, A K Burgess, K E Isenberg, B J van de Wetering, B Oostra.   

Abstract

A genetic linkage study of fifteen families (n = 166) ascertained through probands diagnosed for Tourette syndrome was carried out for the D2-dopamine receptor and flanking loci on chromosome 11q22-q23. Tight linkage was excluded for all probes and regions of exclusion up to +/- 20% recombination were obtained. Overlapping regions of exclusion based upon primary map data permit exclusion of the entire region of the DRD2 locus in Tourette syndrome.

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Year:  1990        PMID： 2335364     DOI： 10.1159/000153914

Source DB:  PubMed          Journal:  Hum Hered        ISSN： 0001-5652            Impact factor:   0.444


  6 in total

Review 1.  The genetics of Tourette syndrome.

Authors:  D L Pauls
Journal:  Curr Psychiatry Rep       Date:  2001-04       Impact factor: 5.285

2.  Exacerbation of motor tic and induction of new tic by haloperidol use.

Authors:  J M Diaz; K G Smith; M Maccario
Journal:  West J Med       Date:  1992-02

3.  No evidence for genetic linkage of Gilles de la Tourette syndrome on chromosomes 7 and 18.

Authors:  P Heutink; B J van de Wetering; G J Breedveld; J Weber; L A Sandkuyl; E J Devor; A Heiberg; M F Niermeijer; B A Oostra
Journal:  J Med Genet       Date:  1990-07       Impact factor: 6.318

4.  Linkage studies on Gilles de la Tourette syndrome: what is the strategy of choice?

Authors:  P Heutink; B J van de Wetering; A J Pakstis; R Kurlan; P Sandor; B A Oostra; L A Sandkuijl
Journal:  Am J Hum Genet       Date:  1995-08       Impact factor: 11.025

Review 5.  The genetics of Tourette syndrome: a review.

Authors:  Julia A O'Rourke; Jeremiah M Scharf; Dongmei Yu; David L Pauls
Journal:  J Psychosom Res       Date:  2009-09-30       Impact factor: 3.006

6.  Progress in the search for genetic linkage with Tourette syndrome: an exclusion map covering more than 50% of the autosomal genome.

Authors:  A J Pakstis; P Heutink; D L Pauls; R Kurlan; B J van de Wetering; J F Leckman; L A Sandkuyl; J R Kidd; G J Breedveld; C M Castiglione
Journal:  Am J Hum Genet       Date:  1991-02       Impact factor: 11.025
  6 in total

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