Literature DB >> 23943463

Generation of bone marrow and fetal liver chimeric mice.

Eda K Holl1.   

Abstract

The creation of bone marrow and fetal liver chimeric mice has proven to be a valuable tool in the field of immunology. Chimeric mice are used to study the contribution of various cell types of hematopoietic versus non-hematopoietic origin in the course of an immune response. In this chapter, we describe a detailed method to obtain bone marrow or fetal liver chimeric mice and assess the efficiency of donor cells to repopulate the hematopoietic compartment of recipient mice.

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Year:  2013        PMID： 23943463      PMCID： PMC3947880          DOI： 10.1007/978-1-62703-496-8_24

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  11 in total

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  7 in total

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