Literature DB >> 23941833

Molecular imaging in pancreatic cancer--a roadmap for therapeutic decisions.

Gabriela Kramer-Marek1, Jesse Gore, Murray Korc.   

Abstract

Pancreatic ductaladeno carcinoma (PDAC) is a deadly cancer characterized by multiple molecular alterations, the presence of an intense stroma, poor perfusion, and resistance to therapy. In addition to standard imaging techniques, experimental imaging strategies, such as those utilizing molecular probes, nanoparticle-based agents, and tagged antibodies are actively being explored experimentally. It is hoped that advances in these technologies will allow for detecting PDAC at an early stage, and could serve to validate experimental therapies, rapidly identify non-responders, and assist in the design of novel therapeutic strategies tailored to the patient's molecular profile.
Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  Molecular imaging; PDAC; Ultrasonography

Mesh：

Year:  2013        PMID： 23941833      PMCID： PMC3902085          DOI： 10.1016/j.canlet.2013.08.008

Source DB:  PubMed          Journal:  Cancer Lett        ISSN： 0304-3835            Impact factor:   8.679


  64 in total

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Authors:  Meir Preis; Murray Korc
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2.  Differentiation of autoimmune pancreatitis from pancreatic cancer by diffusion-weighted MRI.

Authors:  Terumi Kamisawa; Kensuke Takuma; Hajime Anjiki; Naoto Egawa; Tastuo Hata; Masanao Kurata; Goro Honda; Kouji Tsuruta; Mizuka Suzuki; Noriko Kamata; Tsuneo Sasaki
Journal:  Am J Gastroenterol       Date:  2010-03-09       Impact factor: 10.864

Review 3.  The role of PET scanning in pancreatic cancer.

Authors:  Oscar K Serrano; Muhammad A Chaudhry; Steven D Leach
Journal:  Adv Surg       Date:  2010

Review 4.  KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma.

Authors:  John P Morris; Sam C Wang; Matthias Hebrok
Journal:  Nat Rev Cancer       Date:  2010-09-03       Impact factor: 60.716

5.  Role of pancreatic stellate cells in pancreatic cancer metastasis.

Authors:  Zhihong Xu; Alain Vonlaufen; Phoebe A Phillips; Eva Fiala-Beer; Xuguo Zhang; Lu Yang; Andrew V Biankin; David Goldstein; Romano C Pirola; Jeremy S Wilson; Minoti V Apte
Journal:  Am J Pathol       Date:  2010-10-07       Impact factor: 4.307

Review 6.  Pancreatic cancer: understanding and overcoming chemoresistance.

Authors:  Zhiwei Wang; Yiwei Li; Aamir Ahmad; Sanjeev Banerjee; Asfar S Azmi; Dejuan Kong; Fazlul H Sarkar
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2010-11-23       Impact factor: 46.802

Review 7.  Tumor microenvironment and progression of pancreatic cancer.

Authors:  M Erkan; C Reiser-Erkan; C W Michalski; J Kleeff
Journal:  Exp Oncol       Date:  2010-09

8.  Detection of precursor lesions of pancreatic adenocarcinoma in PET-CT in a genetically engineered mouse model of pancreatic cancer.

Authors:  Volker Fendrich; Ralph Schneider; Anirban Maitra; Ilse D Jacobsen; Thomas Opfermann; Detlef K Bartsch
Journal:  Neoplasia       Date:  2011-02       Impact factor: 5.715

Review 9.  Pancreatic cancer: the role of pancreatic stellate cells in tumor progression.

Authors:  Siri Dunér; Jacob Lopatko Lindman; Daniel Ansari; Chinmay Gundewar; Roland Andersson
Journal:  Pancreatology       Date:  2011-01-18       Impact factor: 3.996

10.  In vivo imaging of HIF-active tumors by an oxygen-dependent degradation protein probe with an interchangeable labeling system.

Authors:  Takahiro Kuchimaru; Tetsuya Kadonosono; Shotaro Tanaka; Takashi Ushiki; Masahiro Hiraoka; Shinae Kizaka-Kondoh
Journal:  PLoS One       Date:  2010-12-23       Impact factor: 3.240
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  13 in total

1.  Optimizing live-animal bioluminescence imaging prediction of tumor burden in human prostate cancer xenograft models in SCID-NSG mice.

Authors:  Sangyub Kim; Yong Zhang; Suni Tang; Chongtao Qin; Deepkamal Karelia; Arati Sharma; Cheng Jiang; Junxuan Lu
Journal:  Prostate       Date:  2019-04-08       Impact factor: 4.104

2.  Dual Targeting of Tissue Factor and CD105 for Preclinical PET Imaging of Pancreatic Cancer.

Authors:  Haiming Luo; Christopher G England; Sixiang Shi; Stephen A Graves; Reinier Hernandez; Bai Liu; Charles P Theuer; Hing C Wong; Robert J Nickles; Weibo Cai
Journal:  Clin Cancer Res       Date:  2016-03-29       Impact factor: 12.531

Review 3.  Advances in Diagnostic and Intraoperative Molecular Imaging of Pancreatic Cancer.

Authors:  Willemieke S Tummers; Juergen K Willmann; Bert A Bonsing; Alexander L Vahrmeijer; Sanjiv S Gambhir; Rutger-Jan Swijnenburg
Journal:  Pancreas       Date:  2018-07       Impact factor: 3.327

4.  Ultrasound imaging of splenomegaly as a proxy to monitor colon tumor development in Apc(min716/+) mice.

Authors:  Andrea Hodgson; Eric M Wier; Kai Fu; Xin Sun; Fengyi Wan
Journal:  Cancer Med       Date:  2016-08-03       Impact factor: 4.452

5.  Oridonin-loaded and GPC1-targeted gold nanoparticles for multimodal imaging and therapy in pancreatic cancer.

Authors:  Wenli Qiu; Rong Chen; Xiao Chen; Huifeng Zhang; Lina Song; Wenjing Cui; Jingjing Zhang; Dandan Ye; Yifen Zhang; Zhongqiu Wang
Journal:  Int J Nanomedicine       Date:  2018-10-24

6.  Extracellular acidosis differentiates pancreatitis and pancreatic cancer in mouse models using acidoCEST MRI.

Authors:  Rachel A High; Edward A Randtke; Kyle M Jones; Leila R Lindeman; Jacqueline C Ma; Shu Zhang; Lucia G LeRoux; Mark D Pagel
Journal:  Neoplasia       Date:  2019-11-14       Impact factor: 5.715

7.  Targeting pancreatic ductal adenocarcinoma acidic microenvironment.

Authors:  Zobeida Cruz-Monserrate; Christina L Roland; Defeng Deng; Thiruvengadam Arumugam; Anna Moshnikova; Oleg A Andreev; Yana K Reshetnyak; Craig D Logsdon
Journal:  Sci Rep       Date:  2014-03-19       Impact factor: 4.379

8.  Targeting of the P2X7 receptor in pancreatic cancer and stellate cells.

Authors:  Andrea Giannuzzo; Mara Saccomano; Joanna Napp; Maria Ellegaard; Frauke Alves; Ivana Novak
Journal:  Int J Cancer       Date:  2016-08-29       Impact factor: 7.396

9.  Early Detection in a Mouse Model of Pancreatic Cancer by Imaging DNA Damage Response Signaling.

Authors:  James C Knight; Julia Baguña Torres; Robert Goldin; Michael Mosley; Gemma M Dias; Luisa Contreras Bravo; Veerle Kersemans; P Danny Allen; Somnath Mukherjee; Sean Smart; Bart Cornelissen
Journal:  J Nucl Med       Date:  2019-12-20       Impact factor: 11.082

Review 10.  Translational molecular imaging in exocrine pancreatic cancer.

Authors:  Bart Cornelissen; James C Knight; Somnath Mukherjee; Laura Evangelista; Catarina Xavier; Federico Caobelli; Silvana Del Vecchio; Latifa Rbah-Vidal; Jacques Barbet; Marion de Jong; Fijs W B van Leeuwen
Journal:  Eur J Nucl Med Mol Imaging       Date:  2018-09-17       Impact factor: 9.236
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