Literature DB >> 23939220

DspA from Strongylocentrotus purpuratus: The first biochemically characterized haloalkane dehalogenase of non-microbial origin.

Andrea Fortova1, Eva Sebestova, Veronika Stepankova, Tana Koudelakova, Lenka Palkova, Jiri Damborsky, Radka Chaloupkova.   

Abstract

Haloalkane dehalogenases are known as bacterial enzymes cleaving a carbon-halogen bond in halogenated compounds. Here we report the first biochemically characterized non-microbial haloalkane dehalogenase DspA from Strongylocentrotus purpuratus. The enzyme shows a preference for terminally brominated hydrocarbons and enantioselectivity towards β-brominated alkanes. Moreover, we identified other putative haloalkane dehalogenases of eukaryotic origin, representing targets for future experiments to discover dehalogenases with novel catalytic properties.
Copyright © 2013 Elsevier Masson SAS. All rights reserved.

Entities:  

Keywords:  CD; Catalytic activity; Enantioselectivity; Eukaryotic haloalkane dehalogenase; Gene mining; IPTG; PCA; Principle Component Analysis; Substrate specificity; T(m); circular dichroism; isopropyl β-D-thiogalactopyranoside; melting temperature

Mesh：

Substances：

Year:  2013        PMID： 23939220     DOI： 10.1016/j.biochi.2013.07.025

Source DB:  PubMed          Journal:  Biochimie        ISSN： 0300-9084            Impact factor:   4.079


  8 in total

1.  A Haloalkane Dehalogenase from a Marine Microbial Consortium Possessing Exceptionally Broad Substrate Specificity.

Authors:  Tomas Buryska; Petra Babkova; Ondrej Vavra; Jiri Damborsky; Zbynek Prokop
Journal:  Appl Environ Microbiol       Date:  2018-01-02       Impact factor: 4.792

2.  A Haloalkane Dehalogenase from Saccharomonospora viridis Strain DSM 43017, a Compost Bacterium with Unusual Catalytic Residues, Unique (S)-Enantiopreference, and High Thermostability.

Authors:  Klaudia Chmelova; Eva Sebestova; Veronika Liskova; Andy Beier; David Bednar; Zbynek Prokop; Radka Chaloupkova; Jiri Damborsky
Journal:  Appl Environ Microbiol       Date:  2020-08-18       Impact factor: 4.792

3.  Discovery of Novel Haloalkane Dehalogenase Inhibitors.

Authors:  Tomas Buryska; Lukas Daniel; Antonin Kunka; Jan Brezovsky; Jiri Damborsky; Zbynek Prokop
Journal:  Appl Environ Microbiol       Date:  2016-01-15       Impact factor: 4.792

4.  Ylehd, an epoxide hydrolase with promiscuous haloalkane dehalogenase activity from tropical marine yeast Yarrowia lipolytica is induced upon xenobiotic stress.

Authors:  Chandrika Bendigiri; Smita Zinjarde; Ameeta RaviKumar
Journal:  Sci Rep       Date:  2017-09-19       Impact factor: 4.379

5.  A puzzling homology: a brittle star using a putative cnidarian-type luciferase for bioluminescence.

Authors:  Jérôme Delroisse; Esther Ullrich-Lüter; Stefanie Blaue; Olga Ortega-Martinez; Igor Eeckhaut; Patrick Flammang; Jérôme Mallefet
Journal:  Open Biol       Date:  2017-04       Impact factor: 6.411

Review 6.  Dehalogenases: From Improved Performance to Potential Microbial Dehalogenation Applications.

Authors:  Thiau-Fu Ang; Jonathan Maiangwa; Abu Bakar Salleh; Yahaya M Normi; Thean Chor Leow
Journal:  Molecules       Date:  2018-05-07       Impact factor: 4.411

7.  A putative chordate luciferase from a cosmopolitan tunicate indicates convergent bioluminescence evolution across phyla.

Authors:  Michael Tessler; Jean P Gaffney; Anderson G Oliveira; Andrew Guarnaccia; Krista C Dobi; Nehaben A Gujarati; Moira Galbraith; Jeremy D Mirza; John S Sparks; Vincent A Pieribone; Robert J Wood; David F Gruber
Journal:  Sci Rep       Date:  2020-10-20       Impact factor: 4.379

8.  Violet bioluminescent Polycirrus sp. (Annelida: Terebelliformia) discovered in the shallow coastal waters of the Noto Peninsula in Japan.

Authors:  Shusei Kanie; Daisuke Miura; Naoto Jimi; Taro Hayashi; Koji Nakamura; Masahiko Sakata; Katsunori Ogoh; Yoshihiro Ohmiya; Yasuo Mitani
Journal:  Sci Rep       Date:  2021-09-27       Impact factor: 4.379
  8 in total

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